No abstract

Relevance. Currently, system-wide patterns of development, progression of oral lichen planus have not been studied enough. The questions of substantiation of expedient therapeutic and prophylactic measures for this disease with characteristic risk factors have not been worked out in many respects.Purpose. Identifcation of new system-wide regularities of oral lichen planus based on the development of a model for its development, prevention and treatment.Materials and methods. The study design included: the development of a model for the development, progression, prevention and treatment of oral lichen planus; clinical dental examination of 350 patients with oral lichen planus (the diagnosis was made on the basis of clinical data and the results of fluorescent diagnostics); evaluation of the effectiveness of a set of measures, including the prescription of drugs (Imudon, Kudesan, Tenoten).Results. New system-wide regularities of lichen planus are revealed. For the frst time, the relative frequencies and intensities of transitions of various forms of lichen planus from one to another are estimated. A method is proposed for estimating the moment of saturation of the therapeutic and prophylactic effect of a complex of measures on the oral mucosa with lichen planus using fluorescent diagnostics. The temporal characteristics of this moment were determined during the performance of the therapeutic and prophylactic complex.Summary. The developed model will allow, without signifcant time and material costs, justify therapeutic and prophylactic measures that are expedient for various groups of the population in case of oral lichen planus of the oral mucosa.

Relevance. Methods for assessing the effectiveness of therapeutic and prophylactic measures for smoking groups of periodontal patients now require substantial material costs. They do not take full account of the rapidly changing epidemiological situation, as well as system-wide patterns of development, prevention and treatment of periodontal inflammatory diseases based on a temporary or permanent smoking cessation. At present, they are imperfect as models for the development, progression, prevention and treatment of periodontal inflammatory diseases in smokers, and methods that predict the condition of periodontal disease with a view to quitting smoking. Purpose ― search of perspective ways of substantiation of complex medical-prophylactic measures on the basis of epidemiological analysis of periodontological morbidity in the smoking population Materials and methods. 401 smokers and 400 non-smokers were examined. The examination was carried out according to a standard procedure in compliance with clinical recommendations for the management of dental patients. The smoking group included patients with a smoking experience of more than 3 years. The fact of smoking was confirmed by the data of the concentration of carbon monoxide in the exhaled air using a portable gas analyzer. The design of the study included the development of a model for the development, prevention and treatment of chronic generalized periodontitis in the smoking population, taking into account temporary or permanent quitting. Results. The epidemiological analysis of periodontological morbidity in the smoking population of the city of St. Petersburg on the basis of its own clinical studies and data from the federal service of state statistics was carried out. A model has been developed which makes it possible to promptly predict the periodontal status of the smoking population, taking into account anti-tobacco measures, without significant expenditures. Conclusions. An improved model of chronic generalized periodontitis is proposed. Dentists are advised to identify and differentiate groups of smokers using portable gas analyzers. Along with complex periodontal measures for such groups of patients, it is necessary to conduct direct medical and preventive measures, including using nicotine replacement therapy.

Introduction. The article discusses a new method for estimating the saturation of a therapeutic and prophylactic effect on periodontal on the background of refusal of smoking and its application to assess the parameters of periodontal transitions from the stage of exacerbation to the stage of remission.The objective was to improve the accuracy of low-cost prediction of the effectiveness of interventions in inflammatory periodontal diseases in smoking patients based on the development of a new method for assessing the saturation of therapeutic and prophylactic effects.Methods and materials. To determine the saturation of therapeutic and prophylactic effects on periodontal in smoking patients, it was proposed to estimate the weighted average increase in the reduction of a new series of indicators (concentration of carbon monoxide in exhaled air, clinical indices and frequency of occurrence and nature of exudate of periodontal spaces).Results. The saturation of the therapeutic and prophylactic effect on periodontal on the background of quitting (using anti-tobacco patches) when conducting events with xanthan gel with chlorhexidine or photo-activated disinfection occurs much earlier than the two-week interval. Estimates of the relative frequencies and intensities of therapeutic and prophylactic transitions are obtained when performing procedures against the background of nicotine replacement therapy.Conclusion. The proposed method for assessing the saturation of the therapeutic and prophylactic effect on periodontal in smoking patients allows to take into account additional features of the analyzed process and to carry out a low-cost prediction of the effectiveness of complex therapy.Authors declare no conflict of interest.The authors confirm that they respect the rights of the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.