The formation of a culture of tolerance is one of the tasks of upbringing. Throughout their life, a person learns to be tolerant towards other people and to respect and accept others as they are. It is very important that, in adolescence, a person understands that not only success in life and career, but sometimes life itself, depends on their level of tolerant behavior and consciousness of others. This article is devoted to the topic of tolerance in modern pedagogy, which is the most important component of humane pedagogy. In the light of new socio-economic and political upheavals, the topic of the formation of a culture of tolerance in the process of pedagogical activity is relevant.The purpose of this study is to establish the levels of formation of a culture of tolerance in the process of pedagogical activity.During the analysis, we conclude that the formation of tolerance consists in the passage of three levels of educational results.At the first level, the teacher must give the child "moral knowledge" about what tolerance is, what is the value of modern society, and that there are different cultures, nationalities, religions in the world that can and must

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Acute disorders of cerebral hemodynamics lead to the development of socially and demographically significant diseases, as a result of which they are one of the main health problems requiring a rational pharmacological approach. In the pathogenesis of pathologies of cerebral circulation, in addition to a decrease in blood flow, an important role is played by a violation of the bioelectric activity of brain tissues, which is evidenced by changes in the frequency and amplitude of oscillations on the encephalogram. Pyrimidine derivatives have proven themselves as potential cerebroprotectors, as a result of which we considered them as means capable of correcting electroencephalogram disorders in ischemic brain tissues. In this regard, the purpose of this work was to study the effect of pyrimidine and cavinton derivatives on the change in bioelectric potential under conditions of focal central ischemia in rats. Materials and methods. The study was conducted on 40 male rats of the Wistar line (m = 220–220 g). Focal cerebral ischemia of rats was reproduced by occlusion of the left middle cerebral artery. The animals were divided into 4 equal groups, all groups, except the first, were simulated pathology under chloral hydrate anesthesia (350 mg/kg). The first group – falsely operated rats, the second – individuals of negative control. The reference drug cavinton (3.2 mg/kg) and the pi-rimidine derivative PIR-10 (50 mg/kg) were administered to the third and fourth groups within 3 days after surgery. The electrical activity of the rat brain (delta-, theta-, alpha-, high-frequency beta-range in the frontal and parietal lobes of the left hemisphere) was evaluated after 3 days by electroencephalography (EEG) using the Neuron-Spectrum 1 encephalograph (Neurosoft, Russia). Statistical processing was carried out using the STATISTICA 8.0 application software package (StatSoft, Inc., USA). Results of the study. In the rats of the negative control group, there was a marked deterioration in bioelectric potential, which was noted in an increase in theta and delta rhythms and a decrease in alpha and high-frequency beta rhythms. The introduction of the compound PIR-10 to animals contributed to a decrease in delta rhythm by 39,8% (p < 0,05) (FP1-A1) and 56,3% (p < 0,05) (C3-A1), theta rhythm – by 23,9% (p < 0,05) (FP1-A1) and 39,4% (p < 0,05) (C3-A1), the amplitude of the alpha rhythm increased by 75,3% (p < 0,05) (C3-A1), the high-frequency beta rhythm by 25,9% (p<0,05) (FP1-A1) and 41,4% (p < 0,05) (C3-A1). Findings. The experimental derivative of pyrimidine PIR-10, equally with cavinton, contributed to the restoration of bioelectric rhythm in the form of a decrease in the amplitude of delta and theta rhythms and an increase in the amplitude of alpha and high-frequency beta rhythms in the frontal and parietal regions of the left hemisphere of the rat brain.

The article considers the experience of using "green" technologies in various branches of the economy. World practice shows that introduction and subsequent use of "green" technologies increase the efficiency of a particular branch of the economy. At this, the direction of development and the scope of using "green" technologies differ in different countries. Among the predominant areas of using "green" technologies, it is necessary to mark the construction sector, development of renewable energy sources, infrastructure projects, agriculture. Based on actual data, the predominant role of "green" technologies in the scenario for the development of most foreign countries' economies is shown. "Green" technologies in the world practice have become one of the promising directions in development of most branches of economy. The urgency of using "green" technologies in the Russian economy is caused by the fact that against the background of worsening environmental problems, increasing economic tension, the "green" vector of development will make it possible to solve not only environmental, but economic and social problems as well. The analysis of world experience in the use of "green" technologies in various fields of economy gives the opportunity to consider the "green" vector as one of the priority directions for the development of many sectors of Russian economy.

М.П. Ефремова Изучение адаптогенной активности и токсикологической безопасности экстракта жирного масла семян чернушки Оригинальная статья Original article