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The comparison of hydrogeochemical conditions of Jurassic-Cretaceous sediments of Koltogor- Tolkinskaya suture zone and the adjacent tectonic structures was based on the results of the chemical composition analysis of almost 1,500 groundwater samples. The average values of the overall salinity of subsurface water and their content of basic components of ion-salt and microcomponent composition were compared for Aptian-Albian-Senomanian, Neocomian and Jurassic aquifer complexes of Koltogorsky, Tolkinsky, Yuzhno-Tolkinsky megatroughs and Tagrinsky, Bakhilovsky, Alexandrovsky, Srednevasyugansky megaswells, as well as Nizhnevartovsky, Kaymysovsky arches. Using Sulin’s classification and cluster analysis the type of groundwater was characterized by the hydrogeochemical parameters set. It was defined that the suture zone presence does not directly affect the hydrogeochemical conditions of deep horizons of this zone and adjacent areas.