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A Novel Sunscreen Agent Having Antimelanoma Activity. -A series of dibenzoylmethane derivatives (I) is synthesized and reduced to mono-(II) and dihydroxy compounds (III). The products are evaluated for their sunscreen and cytotoxic activity. Compound (IIIc) appears to be a leading candidate for use as a UV sunscreen agent, also having therapeutical activity against melanoma cells. -(NOGUEIRA, M. A.; MAGALHAES, E. G.; MAGALHAES, A. F.; BILOTI, D. N.; LAVERDE, A. J.; PESSINE, F. B. T.; CARVALHO, J. E.; KOHN, L. K.; ANTONIO, M. A.; MARSAIOLI*, A.