ctinic keratosis (AK) was the most common dermatologic diagnosis among all dermatologist visits in the United States for patients 45 years or older during the period from 1993 to 2010. 1 Risk factors for AK development include older age, male sex, fair skin, lifetime UV light exposure, and sunburns. 2 Actinic keratosis is frequently treated to address potential for malignant transformation, relieve patient symptoms, improve quality of life and cosmetic outcomes, and facilitate diagnosis of keratinocyte carcinoma in settings of field cancerization. 3-7 The estimated burden of AK and its treatment have varied significantly. 8,9 The American Academy of Dermatology Burden of Skin Diseases reports showed that 10 million to 39.5 million Americans sought care for actinic damage, which

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