The authors report the onset of wheezing and dyspnea in a 32-year-old, nonasthmatic male who was receiving propranolol for chronic migraine headaches of 20 years' duration. The symptoms first appeared during the "cold season"; the diagnosis was bronchitis. After three months without propranolol, the patient, prompted by continuing migraine headaches, again took the drug (40 mg bid). Within 48 hours he complained of rhinitis that rapidly progressed to wheezing, resembling bronchitis. Other reports in the literature are discussed.
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