(2018) Identification and prediction of the fertile window with a new web-based medical device using a vaginal biosensor for measuring the circadian and circamensual core body temperature, Gynecological Endocrinology, 34:3, 256-260, DOI: 10.1080/09513590.2017 Fertility awareness-based (FAB) methods represent a term that includes all family planning methods that are based on the identification of the fertile window. They are based on the woman's observation of physiological signs of the fertile and infertile phases of the menstrual cycle. The first approach consists basically in symptothermal methods accompanied by cervical mucus measurements and clinical menstrual cycling data recording. The second most often used methods are the urinary measurement of E3G and luteinizing hormone (LH) with a personalized computer system. Hence these systems lack the efficacy of the continuous circadian and circamensual measurement of the core body temperature. Only this approach enables the accurate detection of the ovulation during the fertile window. A new medical device called OvulaRing has been developed to fill this gap. In the present study, the system and its first clinical results are presented. OvulaRing is a medical device used just like a tampon. The device is a vaginal ring of evatane that contains an integrated biosensor. This sensor measures continuously every 5 min the core body temperature throughout the entire cycle. This device allows a circadian and circamensual intravaginal exact measurement. With this system, 288 measurements are created per day. The system can detect retrospectively and predict prospectively the fertile window of the users. One hundred and fifty eight women aged between 18 and 45 years used this medical device in an open non-randomized clinical study for 15 months. A total of 470 cycles could be recorded and were able for analysis. By the same time in a subgroup of patients, hormonal assessments of LH, follicle-stimulating hormone, estradiol and progesterone as well as vaginal ultrasound were performed in parallel between the 9th and the 36th day of the cycle. The validation error due to software errors was 0.89% for the retrospective analysis; that means that the accuracy for the detection of the ovulation was 99.11%. Accuracy of 88.8% for a window of 3 days before ovulation, the day of ovulation and the 3 days after ovulation was achieved for the prospective analysis. In the subgroup of woman with recorded pregnancies, it could be shown that after 3.79 months of use (median) pregnancies were observed. In 67.72% in up to 3 months, in 16.36% between 3 and 6 months of use, in 7.27% between 7 and 9 months, in 5.45% between 10 and 12 months and in 1.82% between 13 and 15 months of use of the system. With this new web-based system, a precise determination of the fertile window even in women with ultralong cycles (>35 days) could be detected independently of their personal live circumstances. Exact determination of the fertile window is herewith possible so that OvulaRing represents an evolut...
Autor artykułu analizuje wybrane przykłady działalności Iwana Franki oraz Łesi Ukrainki, zwracając uwagę na te jej przejawy, których centrum jest kwestia tożsamości ukraińskiej, potrzeba jej budowania i umacniania, bo tylko dzięki temu Ukraińcy i Ukraina są w stanie proklamować swoją odrębność. Pisarze, reprezentujący rozdzielone politycznymi granicami części Ukrainy, realizują w swojej działalności narracje antykolonialne.
The first lady of the Ukrainian poetry, as she is often described, Lesia Ukrainka (1871–1913) left not only a very valuable poetical heritage (poetry, dramaturgy, prose, literary criticism) but also an extremely interesting epistolography, thanks to which researchers can better understand her literary works and extraordinary personality, which can be represented by many images: an image of a woman, a daughter, a friend, a beloved, and a Ukrainian patriot. A letter is a specific literary genre which is now widely studied by researchers. Lesia Ukrainka’s letters are characterised by a unique epistolographic narration in which she presented her life and work. Her letters are very vivid, spontaneous, often have the form of polemics or confessions, contain her observations regarding the psychology of creativity as well as some draft s of her upcoming literary works. To some extent, they may serve as the record of the times and the lives that the contemporary Ukrainian intelligence lived. But first and foremost, Lesia Ukrainka’s letters are the source of knowledge about the poetess herself, her numerous roles, and the way her personality was created as a result of many hardships, dilemmas, and struggle. The present paper aims at presenting the selected roles of Lesia Ukrainka in order to draw her psychological portrait, to show her individuality, and to bring closer her image not only of a great poetess, which is quite commonly known, but the image of the woman who lived her own life and destiny.
Авторка статті аналізує драму сучасного українського письменника Олександра Ірванця Брехун з Литовської площі, звертаючи увагу на проблеми національної тотожності, мови, ідентичності тощо. Драма О. Ірванця становить дзeкрало, у якому виразно відбиваються найболючіші проблеми української сучасності.
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