Highlights
c-Myb attenuates NF-κB activity in breast cancer.
Interaction with co-activator p300 is required for NF-κB suppression by c-Myb.
c-Myb negatively regulates IL1a transcription in several ER- breast cancer cell lines.
Inhibition of IL1α expression mediates the anti-inflammatory effect of c-Myb.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.