Background: Acne vulgaris is a pilosebaceous gland disease usually affecting people from puberty to young adulthood due to hormonal changes, but the exact relationship of various hormone to acne is not known. Aims:-The present study has been planned to find out the association of hormonal status with the different grades of acne vulgaris female patients.. Methods: Fifty patients each of Mild (group I), Moderate (group II) and Severe Acne Vulgaris (group III) in age group 15-40 years were included as cases. The fasting blood samples were collected on the second day of menstrual cycle of the patient and before the start of treatment. Written and informed consent was taken from all subjects in the cases and control groups after explaining about the details of the study. Results: Levels of Luteinizing Hormone (LH), Estrogen, Testosterone, Insulin, Follicle Stimulating Hormone (FSH) and Prolactin in different grade of acne vulgaris patients were compared with control groups. Statistical analysis was done using Kruskal Wallis test and ANOVA. Conclusion: Level of LH, Estradiol,Testosterone andInsulin may be studied in cases resistant to conventional treatment of acne in women while the levels of FSH and prolactin, need not to be studied.

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Background: The uric acid in serum (SUA) is significantly related with cardiovascular disease, it is proved by clinically. The increased level of uric acid in the serum lead to highly platelet reactivity mediating inflammation and stimulate of smooth muscle cell production which probably degrades acute thrombosis. Methods: The blood samples were collected and sent to biochemistry laboratory for estimation of uric acid. This study conducted in the Departments of Biochemistry, Dr. Ram Manohar Lohia Medical College Lucknow. Results: In this study 200 patients included with acute myocardial infarction. Among the 200 patients, 148 (74%) were male and 52 (26%) were female. Among the 25-70 Age group , most of people from 56-70 age group. Mean of uric acid level in male cases was 5.6 and female cases was 5.2 , male controls was 4.2 and female controls was 3.6. Conclusion: The uric acid level in the serum are high in patients which had acute myocardial infarction as compare to other persons. It is also higher with the killips classes. The Killips classification and uric acid level in the serum is a good analyst of mortality after acute myocardial infarction, if is combined.

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