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Methodological approaches to the analysis and assessment of marketing competitive advantages of pharmacy networksTo determine the right strategic course is the most responsible thing for any company. Therefore, it is extremely important for management to carefully approach to development and implementation of the strategy considering many internal and external factors and focusing on a number of factors.Aim. To develop methodological approaches in order to identify strengths and weaknesses, assessment of their importance, as well as to determine the marketing competitive advantages of pharmacy networks.Materials and Methods. To solve this task a survey of 402 employees of 30 pharmacy networks was carried out. The following methods were used in the study: Friedman two-way analysis of variance of dependent samples; Wilcoxon's criterion of related samples with Benjamini-Hochberg correction for multiplicity; Kendall's coefficient of concordance; verbal numeric rating scale of Harrington and Margolin; cluster analysis; analysis using Pearson criterion c2 and maximum likelihood criterion c2; Kruskal-Wallis test.Results. The analysis of the priority of competing pharmacies strengths was conducted: in the first cluster (small pharmacy networks) the greatest importance is given to such competitive factors as convenience of location of the pharmacy, affordability of goods and services, as well as the width of the range of drugs and parapharmaceutical products; in the second cluster (medium pharmacy networks) the highest scores are given to availability of additional services and convenient work schedule; the rate and quality of service, affordability of goods and services, availability of professional development programs for the staff, the width of the range of drugs and parapharmaceutical products are the priorities in the third cluster (large and mega pharmacy networks).Conclusions. The results of the studies conducted should be considered when forming competitive strategies of pharmacy networks taking into account their type.Key words: pharmacy networks; the strengths of competitors; width of the drug range; affordability of goods and services; convenience of location of the pharmacy; effectiveness of the pricing policy.Ж. В. Мала, О. В. Посилкіна, М. М. Нессонова Методичні підходи до аналізу й оцінки маркетингових конкурентних переваг аптечних мереж Визначення правильного стратегічного курсу є найбільш відповідальною справою для підпри-ємства. Тому менеджменту вкрай важливо підійти зважено до процесу розробки та реалізації стра-тегії, врахувавши багато внутрішніх і зовнішніх чинників та акцентувавши увагу на низці факторів.Мета: розробка методичних підходів до визначення сильних і слабких сторін, оцінки їх ваго-мості, визначення маркетингових конкурентних переваг аптечних мереж.Матеріали та методи. Для вирішення поставленої мети нами було проведено анкетування 402 співробітників 30 аптечних мереж. У процесі дослідження були використані такі методи: дво-факторний аналіз Фрідмена залежних вибірок; критерій Уїлкоксона в...

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20 % of ischemic stroke appear to originate from carotid artery atherosclerotic disease. Serum biomarkers reflecting the activity of atherosclerotic process and may help for estimate risk of acute cerebrovascular events. Several serum inflammatory markers have been proposed for risk assessment, but their prognostic role less known. The aim of this study is to clarify the prognostic value of biomarkers of atherosclerosis lipoprotein-associated phospholipase A2 (Lp-PLA2) and E-selectin in patients with symptomatic and asymptomatic carotid stenosis. Materials and methods. The study involved 106 patients with atherosclerotic carotid stenosis >50 % (74 men and 32 women, mean age 62.6±0.9) from which 76 symptomatic (35 with acute ipsilateral atherothrombotic stroke and 41 after carotid endarterectomy) and 30 asymptomatic patients. The control group consisted of age- and sex-matched 20 healthy subjects. The level of serum Lp-PLA2 and E-selectin was determined using a commercially available enzyme-linked immunosorbent assay kit. Results. The level of Lp-PLA 2 was in general significantly higher (p<0.05) in patients groups than in the control group and most high Lp-PLA2 concentration was in groups of symptomatic patients who underwent carotid endarterectomy. The level of E-selectin in the study patients was significantly higher than in the control group (p<0.05). The correlation of Lp-PLA 2 with E-selectin was significant for total patients (R=0.365664, p=0.00085) and group after carotid endarterectomy (R=0.429143, p=0.01796), but not for asymptomatic group (p>0.05). Receiver Operating Characteristics curves of logistic regression models which takes into joint both indicators was specificity and sensitive for predicting the occurrence of ischemic stroke. Conclusion. Conducted study show that the levels of Lp-PLA 2 and E-selectin have a significant impact on the development of stroke in patients with atherosclerotic carotid stenosis and can be used to predict it. A multidimensional model of the dependence of the probability of stroke on a linear combination of Lp-PLA 2 and E-selectin allows to obtaining significantly higher characteristics of the accuracy of stroke prediction than models with each factor alone.