Musculoskeletal disorders (MSDs) are conditions that can affect muscles, bones, and joints. These disorders are very painful and severely limit patients' mobility and are more common in the elderly. MSCs are multipotent stem cells isolated from embryonic (such as the umbilical cord) and mature sources (such as adipose tissue and bone marrow). These cells can differentiate into various cells such as osteoblasts, adipocytes, chondrocytes, NP-like cells, Etc. Due to MSC characteristics such as immunomodulatory properties, ability to migrate to the site of injury, recruitment of cells involved in repair, production of growth factors, and large amount production of extracellular vesicles, these cells have been used in many regenerativerelated medicine studies. Also, MSCs produce different types of EVs, such as exosomes, to the extracellular environment. Exosomes reflect MSCs' characteristics and do not have cell therapy-associated problems because they are cell-free. These vesicles carry proteins, nucleic acids, and lipids to the host cell and change their function. This review focuses on MSCs and MSCs exosomes' role in repairing dense connective tissues such as tendons, cartilage, invertebrate disc, bone fracture, and osteoporosis treatment.

Nanoreactors are a type of chemical reactor that is used mostly in nanotechnology and nanobiotechnology. These unique reactors are critical to the operation of a nano foundry, which is essentially a foundry that produces goods on a nanoscale. Active sites, such as transitional metal species, can also be added to nanoreactors. In this situation, the NR’s limited area might impact reaction rate and mechanism by increasing the contacts between reactants and active sites and changing the concentration of the reactant at the active site. Immobilization of chiral active centers inside porous materials has received a lot of interest in this context, and there have been a lot of publications proving the benefits of nano space confinement in chemical processes. The specific mechanism in which enantioselectivities are strengthened has been clarified using molecular dynamics simulations. Nanoreactors are nanometer-sized chambers with the potential to improve chemical conversions by shielding catalysts from external effects and encapsulating reactors and catalysts in a tiny space for an extended period of time. Natural and synthetic nanoreactors are the two types of nanoreactors that can be found in general. The first group has a more selective function while also having a more complicated structure, whereas the second group has more variation and a simpler structure. Synthetic nanoreactors have so far been made with a variety of molecules and large types of molecules. The space inside the nanoreactors is a good environment for the production of various nanostructures, in addition to a wide range of chemical reactions. When chemical reactions are carried out in confined spaces with nanometer dimensions and micrometer volumes, the kinetics and the entire process path are altered. Nanoreactors are restricted areas used to execute specialized chemical processes. In the cells of living organisms, numerous simultaneous reactions are based on the same concept. As a result, various biological and chemical structures with nanoreactor characteristics are used in this strategy.

This research is based on a phenomenon that occurs in State Detention Centers in Indonesia. It attempts to test the relation among proactive personality (PP), proactive work behavior (PWB), job satisfaction (JS) and role breadth self-efficacy (RBSE) variables. With a quantitative approach using AMOS, this study took data from 455 respondents from Detention Centers in Indonesia. The results show that PP, JS and RBSE have direct effect on PWB. Further findings will be discussed. The results are expected to increase the understanding of PWB and can be the basis for the human resource management team to decide better approach to build PWB in the organization and eventually implement appropriate policy.

This study for the first time provides insight into the bacterial community in the benthic region of the Off‐Terengganu Coastline, which is considered to be anthropogenically polluted due to heavy fishing vessel commotion. Subsurface bacteria were randomly collected from two locations at different depths and were examined using the 16S rDNA V3‐V4 marker gene on the Illumina™ Miseq platform. In addition, the physiochemical parameters of the sediment were also measured. Surprisingly, the results show a high diversity of sulfur‐oxidizing bacteria in the surveyed area, where Sulfurovum sp. was identified to predominate the overall bacterial community. The physiochemical parameters reveal insufficient evidence of hydrothermal vents in the surveyed area. However, there are traces of hydrocarbon pollutants such as gasoline, diesel, and mineral oil in this area. It is assumed that sediment accumulation in the lee of breakwater plays an important role in trapping the runoff from the nearby harbor, which includes oil spills. Based on the common knowledge, Sulvurofum sp. is a native bacterium that exists in deep hydrothermal vents and volcanic territories. Although the reason for the abundance of Sulfurovum sp. in the surveyed area is still unclear, there is a possibility that metabolic adaptation plays an important role in regulating hydrocarbon pollutants for survival. The work presented in this paper therefore has profound implications for future studies on Sulfurovum sp. versatility. However, future research is needed to strengthen the findings of this study and to provide a better evidence regarding the metabolic response of this bacterium toward hydrocarbon pollutants.

Employee creativity is important for TV companies because it can improve organizational performance and increase success and survival based on the ability to create innovations. In response to this, field reporters who work for TV companies also need high creativity in facing the challenges of their work and in creating innovations. This research aims to test the roles of perceived organizational support, proactive personality, the meaning of work, and work engagement in affecting employee creativity. The total numbers of respondents were 119 selected from 14 private television companies in Indonesia. The method in this study is a quantitative approach using the Partial Least Square (PLS) analysis tool with the SmartPls 3.0 application. Most of the hypotheses of this study show significant results. However, there is one finding that a proactive personality is not able to strengthen employee creativity. This indicates that employees’ behavior at work is sometimes different from the personality. This study is the first to look at news reporters’ employee creativity using the suggested model. As a result, organizations can use the study’s findings as a starting point to determine the best strategy for fostering creativity within their workforce.