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The advantages of CMOS over CCD image sensors are low-power consumption, single supply voltage, and on-chip system integration. However, CMOS image quality is below that of CCD, especially for low light level imaging. This CMOS image sensor uses high-gain adaptive column amplifiers and pinned photodiode technology with an enhanced pixel driving technique. The dynamic range determined by the random noise, the fixed pattern noise and the saturation signal levels are shown to be comparable to the standard CCD image sensor.