We present the design parameters, production process, and in-flight performance of the X-ray telescope (XRT) onboard Suzaku. The imaging capability is significantly improved over the ASCA XRT, which had half-power diameters of ${3\rlap {.}{}^{\mathrm {\prime }}6}$, to ${1\rlap {.}{}^{\mathrm {\prime }}8}$–${2\rlap {.}{}^{\mathrm {\prime }}3}$ for all four XRT-I modules. The optical axes are found to be distributed within a radius of ${1\rlap {.}{}^{\mathrm {\prime }}3}$, which makes the observation efficiency of all the XRTs more than 97% at the XIS-default observing position. The vignetting over the XIS field of view predicted via ray-tracing coincides with that measured for observations of the Crab Nebula to within $\sim 10\%$. Contemporaneous fits of a power law to all of the XIS spectra of the Crab Nebula taken at the two standard observing positions (XIS/HXD-default positions) gives a flux consistent with that obtained by Toor and Seward (1974, AJ, 79, 995) to within $\sim 2\%$. The pre-collimator on the top of each XRT module successfully reduces the intensity of the stray light from the $20'$ and $50'$-off directions down to the level of pre-flight expectations.

No abstract

Low-temperature transport measurements have been carried out on single-wall carbon-nanotube quantum dots in a weakly coupled regime in magnetic fields. Four-electron shell filling was observed, and the magnetic field evolution of each Coulomb peak was investigated. Excitation spectroscopy measurements have revealed Zeeman splitting of single particle states for one electron in the shell, and demonstrated singlet and triplet states with direct observation of the exchange splitting at zero-magnetic field for two electrons in the shell, the simplest example of Hund's rule.

We examined the role of p38 mitogen-activated protein (MAP) kinase in the tumor necrosis factor(IL-6) and interleukin-8 (IL-8) in fresh rheumatoid synovial fibroblast (RSF) cultures concomitantly with the induction of p38 MAP kinase activity. Pretreatment of RSF with a specific p38 MAP kinase inhibitor, SB203580, blocked the induction of IL-6 and IL-8 without affecting nuclear translocation of nuclear factor U UB (NF-U UB) or IL-6 and IL-8 mRNA levels. These findings suggest that p38 MAP kinase inhibitor may have synergistic, rather than additive, effect for the treatment of rheumatoid arthritis.z 2000 Federation of European Biochemical Societies.