Cortes sagitais oblíquos do VE com a via de saída/raiz da aorta. As imagens demonstram lesões significativas no TCE, DA e CD (setas amarelas), determinando déficit perfusional no miocárdio, notadamente na parede anterior 76 Lista de tabelas Lista de tabelas _______________________________________________________________ Tabela 1 -Características epidemiológicas e clínicas da amostra 36Tabela 2 -Dados referentes à dose de radiação do protocolo PET-CT 82 Rb + AngioTC/EC 40 Tabela 3 -Dados do escore de cálcio total e por vaso 43Tabela 4 -Dados do escore de cálcio. Faixas de estratificação por paciente (n=54) 44Tabela 5 -Dados do escore de cálcio. Faixas de estratificação por vaso (n=216) 44Tabela 6 -Dados do escore de cálcio. Faixas de estratificação por paciente modificadas/agrupadas (n=54) 45Tabela 7 -Avaliação anatômica das artérias coronárias. Classificação dos graus de estenose por paciente (n=54) 46Tabela 8 -Avaliação anatômica das artérias coronárias. Classificação dos graus de estenose por segmento (n=864) 47Tabela 9 -Avaliação anatômica das artérias coronárias. Classificação da composição das placas coronarianas nos segmentos com lesão aterosclerótica (n=148) 47Tabela 10 -Medidas de concordância entre resultados do EC (400) e do PET-CT (RFC) 51Tabela 11 -Medidas de concordância entre resultados do EC (600) e do PET-CT (RFC) 51Tabela 12 -Medidas de concordância entre resultados da AngioTC (70%) e do PET-CT (RFC) 52Tabela 13 -Medidas de concordância entre resultados da AngioTC (50%) e do PET-CT (RFC) 52 Introduction: Coronary artery disease (CAD) persists with high morbidity and mortality. Several non-invasive diagnostic imaging modalities are available for its evaluation, including coronary calcium score (CS), coronary CT angiography (AngioCT) and positron emission tomography with rubidium ( 82 Rb PET-CT), with excellent sensitivity and specificity. The integration of these methods into a hybrid examination allows delineating the anatomical and functional impact of atherosclerosis, enabling more accurate diagnoses. Objective: To evaluate coronary anatomy and myocardial perfusion of patients with suspected or known CAD with hybrid technology ( 82 Rb PET-CT and AngioCT/CS), testing the hypothesis of the greater accuracy of the hybrid method in relation to the isolated methods, correlating with myocardial infarction/cardiac death outcome after 24 months. Methods: Fifty-four consecutive patients referred from the Cardiology outpatient clinics of the Heart Institute (InCor-HCFMUSP) to perform CAD assessment in a hybrid study in the Department of Nuclear Medicine of InCor, between May and October 2013, were enrolled. The coronary atherosclerotic burden was accounted by CS; the amount of coronary lesions, stenosis severity and plaque composition were evaluated through AngioCT; 82 Rb PET-CT perfusional analysis was evaluated through the rest and dipyridamole stress summed difference score (SDS) and the coronary flow reserve (CFR) was considered impaired when < 2mL/min/g. After 24 months, the composite outcome of my...