Recently a big interest arises to the automated diagnosis and digitalization of clinical data. The purpose of this article is to present treatment algorithm and software system for Problematic Skin Wounds (PSW) by using Platelet-Rich Plasma (PRP), based on the first study on platelet-rich plasma application carried out in Bulgaria. PSW-PRP-Project software system was developed for entering and processing medical data during PRP treatment, visualization of general patient information, treatment trend, as well as a module for training specialists through the created database. For a period of seven years around 100 patients have been treatment at the Department of Orthopaedics and Traumatology, UMBAL KANEV Ruse AD, by applying platelet-rich plasma. The algorithm for the use of platelet-rich plasma for treating problematic skin wounds allows for the proper and accurate treatment of patients with various problematic skin wounds with the purpose of solving the therapeutic problem and their complete recovery. The procedure’s course is determined based on assessment on three digital criteria TWS, TAS and TSWD. The algorithms are based on our results, obtained for the first in Bulgaria while treating problematic skin wounds by using platelet-rich plasma and successfully treating 92.78% of patients to full recovery.

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This article presents the main algorithms and the methodology for the development of the evaluation criteria and the results of the work of the program environment developed for evaluation and analysis of the electrocardiographic signals in the preventive control of clinically healthy people after emotional or physical stress for the purpose of diagnosing of current disorders in the cardiac activity. The presented structure combines a new approach to building an electronic system for assessing individual medical information from the real life of healthy people and a specific method for analyzing the results. The purpose of preventive control is to preserve human health through early and timely assessment of its current health status.

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The paper presents a concept of application of electronic modeling in the development of e-Health systems for prevention in the diagnosis of problematic skin wounds, which include prevention and treatment, allowing uniformity in the assessment and increase the reliability of treatment tools to achieve a full life without pain, risk, and stress. Health and disease are two phases, changing smoothly or dramatically. It is to this uniqueness of the influences for their direct or indirect management that the research is directed - providing the practicing medical specialists with an opportunity for alternative and adequate diagnostics to ensure the subsequent normal life of the patient. The developed e-Health systems have been applied in the training of specialists in the specialties "Midwife" and "Nurse" and in the specialty "Electronics" at the University of Ruse. They are used in practical training of future doctors in UMHAT KANEV Ruse.