We compared PCR results from SARS-CoV-2-positive patients tested in the community in France from 14 June to 30 July 2021. In asymptomatic individuals, Cq values were significantly higher in fully vaccinated than non-fully vaccinated individuals (effect size: 1.7; 95% CI: 1–2.3; p < 10−6). In symptomatic individuals and controlling for time since symptoms, the difference vanished (p = 0.26). Infections with the Delta variant had lower Cq values at symptom onset than with Alpha (effect size: −3.32; 95% CI: −4.38 to −2.25; p < 10−6).

SARS-CoV-2 viral dynamics in infections with Alpha and Beta variants of concern in the French communityWe read with interest the article by Tang et al. on the multiple introductions of variant B.1.351 into the UK. 1 As SARS-CoV-2 variants of concern rapidly spread internationally, it is important to

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Article reçu le 01 mars 2021, accepté le 09 avril 2021 the TDRs is 66%. Although, a high number of asymptomatic patients among carriers of SARS-CoV-2, we have estimated a specificity of 93% for our test.Conclusions: Performance in terms of sensitivity and specificity of the TDR, as assessed in practice, are inferior to those given by the manufacturer, which raises several questions. What is the impact of falsely negative results for patients carrying a high viral load? Are the implemented measures sufficient to prevent the epidemic?