Background: The greenhouse and field studies were carried out to assess the effect of different rates of poultry manure (PM), pig slurry (PS) and the recommended NPK fertilizer on some soil physico-chemical properties and okra yield of coarse-textured Ultisols in Nsukka, southeastern Nigeria. Methods: The PM and PS were applied at three different rates (10, 20 and 40 t ha-1) as well as no amendment as control and the recommended NPK fertilizer (300 kg/ha) and replicated five times. Soil and agronomic data collected were analyzed for variance (ANOVA) using Genstat 4.0.Result: The PM and PS significantly (p less than 0.05) improved soil pH, soil organic matter, available phosphorous, total nitrogen, aggregate stability, mean weight diameter, bulk density, porosity and saturated hydraulic conductivity in greenhouse and field studies. Significant improvement in CEC was obtained in the field study. The PM and PS significantly (p less than 0.05) improved agronomic parameters e.g. plant height, number of leaves, biomass weight and yield of okra than the control. Poultry manure showed its superiority over other amendments in improving soil and agronomic properties. The study recommended 20 t ha-1 of PM and 40 t ha-1 of PS for sustainable soil and optimum productivity of okra in Nsukka, southeastern Nigeria.