Intraoperative spectral domain optical coherence tomography was comparable with retinal dyes in confirming success after membrane peeling. However, the visualization of flat membranes was better after staining.

Our measurements indicate that diurnal ChT variation may exist, but is less relevant than previously proposed by studies using single location imaging. Sattler's layer shows diurnal variation in line with ChT.

Eyes affected by AAU demonstrate an increase in ChT before and a subsequent decrease after therapy while retinal thickness seems unaltered by disease and therapy. ChT might be a useful biomarker in monitoring posterior involvement and response to therapy in patients with AAU.

Purpose: To prospectively compare microvascular changes of internal limiting membrane (ILM) peeled and nonpeeled eyes in patients with idiopathic epiretinal membranes using optical coherence tomography angiography.Methods: Forty-two patients with epiretinal membranes underwent vitrectomy with (n = 22) or without ILM peeling (n = 20). The mean superficial capillary plexus foveal avascular zone area change between preoperative and three-month postoperative readings served as the main outcome measure. Secondary outcome parameters included mean changes in superficial capillary plexus parafoveal vessel density, central foveal thickness, retinal volume, and best-corrected visual acuity.Results: Mean superficial capillary plexus foveal avascular zone area change (mm 2 ) was 59 ± 74 in the ILM nonpeeling group compared with 212 ± 86 in the ILM peeling group (P = 0.007). Similarly, mean superficial capillary plexus parafoveal vessel density change (%) was higher in the ILM nonpeeling group (ILM nonpeeling 4 ± 4, ILM peeling 22 ± 6, P = 0.003). The mean retinal volume reduction was higher in the ILM peeling group, and this difference also reached statistical significance (P = 0.036). There were no intergroup differences in mean central foveal thickness change and mean best-corrected visual acuity change (P = 0.409 and P = 0.440, respectively). Epiretinal membrane/ILM separation was achieved in 23 of 51 patients. Conclusion:The macular microvasculature demonstrated more remodeling in the ILM nonpeeling group after three months.