Amaranthus is a C4 plant tolerant to drought, and plant diseases and a suitable option for climate change. This plant could form part of every region’s cultural heritage and can be transferred to the next generation. Moreover, Amaranthus is a multipurpose plant that has been identified as a traditional edible vegetable endowed with nutritional value, besides its fodder, medicinal, nutraceutical, industrial, and ornamental potentials. In recent decade Amaranthus has received increased research interest. Despite its endowment, there is a dearth of awareness of its numerous potential benefits hence, it is being underutilized. Suitable cultivation systems, innovative processing, and value-adding techniques to promote its utilization are scarce. However, a food-based approach has been suggested as a sustainable measure that tackles food-related problem, especially in harsh weather. Thus, in this review, a literature search for updated progress and potential uses of Amaranthus from online databases of peer-reviewed articles and books was conducted. In addition, the nomenclature, nutritional, and nutraceutical value, was reviewed. The species of focus highlighted in the review include, A. blitum, A. caudatus, A. cruentus, A. dubius, A. hypochondriacus, A. spinosus, A. thunbergii, A. tricolor, and A. viridis.
