Stream sediment geochemical survey was carried out in Boyo area, samples collected and analyzed for major, trace and rare earth elements using ICP-MS method. Minerals present in concentrates include gold, zircon, muscovite. The grain size of gold varies from 0.125 to 1 mm, their shape ranges from sub-angular to angular. Gold grains are of two categories: the first category includes those that are distal to the source, the second category comprises those that are proximal to the source. Fe2O3, Al2O3 and SO3 are dominant major elements in stream sediment, sediments are depleted in Nb and Mo. Gold (8440 to > 10000 ppb) has the highest concentration, the Au/Ag (av.: 14.16) ratio exhibits unusual value greater than the value of the upper lithosphere. Sediments ranged into low Ag (0.062 to 8.47 ppm) and high Ag (20 to 51.3 ppm) content, and all of this suggests that the Boyo gold grains result from two sources or derived by two geological processes; the sulphidation was the dominant mechanism of gold ore deposition. Ag-Au-Bi-Cu constitutes the mineralization factor and the chalcophile elements Ag, Bi and Cu serve as potential pathfinders for Au in the Boyo area. The presence of these elements in the same factor suggests that gold is associated with sulphide minerals. Ag-Hg-W association is related to the hydrothermal alteration of wall rock. The association Ag-Au-Bi-Cu indicates a typical primary mesothermal sulphide ± gold mineralization paragenesis. The Boyo mature sediments derived from intermediate igneous sources that were deposited in a passive margin environment.