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Outcome of most of the biliary and pancreatic malignancy is not good. Demography and involvement of different sites of these malignancies by endoscopic retrograde cholagiopancreatography (ERCP) are not widely studied in Bangladesh. We have studied ERCP based different biliary and pancreatic malignancy and their demographic characteristics.

Background: Insulin resistance and diabetes mellitus have been detected in patients with chronic liver diseases (CLD); however, there is paucity of information regarding these comorbidities in liver disease patients of Bangladesh.Materials and methods: Thirty patients with hepatitis B virus (HBV)-related CLD and 30 patients with hepatitis C virus (HCV)related CLD were checked for existence of insulin resistance and diabetes mellitus. Results:The mean fasting serum glucose in HBV-related CLD and in HCV-related CLD were 4.37 ± 0.58 and 4.6 ± 0.59 mmol/l, respectively (p = 0.781). The levels of fasting serum insulin levels ZHUH ȝ8PO LQ +%9UHODWHG &/' DQG LQ HCV-related CLD (p = 0.013). The cutoff value of HOMA-IR was 1.73. The mean HOMA-IR of HBV-and HCV-related CLD were 1.35 ± 0.44 and 1.89 ± 0.71 respectively (p = 0.001). Conclusion:It seems that insulin resistance is prevalent among HCV-related CLD patients in Bangladesh. This pilot study indicates that insulin resistance and diabetes mellitus should be checked in all patients of HCV-related CLD during their management.

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Chronic liver disease is one of the common hepatobiliary problems worldwide. A major portion of the cases of chronic liver disease presents as a sequel of hepatotrophic viral infection specially hepatitis B and hepatitis C virus. Hepatitis B virus infects more than 350 million people worldwide and it is a leading cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma [1]. On the other hand hepatitis C virus infects an estimated 170 million people worldwide and it represents a viral pandemic and mostly causes chronic infection leading to cirrhosis in 15-20% of those [2]. In Bangladesh the prevalence of chronic viral hepatitis [3,4] is quite signifi cant. It has been observed that a large number of people in Bangladesh suffer