The non-enzymatic electrochemical sensing of hydrogen peroxide (H 2 O 2 ) is described. This study utilized a 3D bicontinuous nanoporous platinum-gold alloy-based sensor (NPÀ Pt(Au) electrode), which has a morphology that resembles a molecular sieve. SEM and CV were used to evaluate the morphological and electrochemical characteristics of the NPÀ Pt(Au) electrodes. The cathodic voltammetric response of H 2 O 2 was enhanced at the NPÀ Pt(Au) as compared to planar Pt electrodes. The nanoporous electrode was able to maintain the H 2 O 2 voltammetric profile even in the presence of the biofouling agent, serum albumin. Its application as a nonenzymatic sensor for the amperometric measurement of H 2 O 2 was explored.