30-60% patients with skin disorder estimated to have psychiatry comorbidity. Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous follicles with global prevalence around 70-80%. To assess stress, anxiety and depression in patients of acne and their correlation with acne severity. Patients who received diagnoses of acne vulgaris from Dermatology OPD and willing to participate in study where included. Acne severity was assessed using Global Acne Grading System. (GAGS). Patients were assessed for psychiatry morbidity using Hindi version of Depression Anxiety Stress Scale- 21 item (DASS 21). Statistical analysis was done by SPSS version 20.0. Out of 46 patients included in study, 23 (50%) patients reported having mild stress, 7 (15.2%) had moderate and 2 (4.3%) had severe stress. 14 (26.1%) patients reported having mild anxiety and 8 (21.7%) had moderate anxiety. Depression was found in 9 (19.5%) patients as 7 (15.2%) had mild and 2 (4.3%) had moderate depression. As per GAGS, 19 patients had mild acne, 16 had moderate, 8 had severe and 3 had very severe acne. Significantly high proportion of patients with acne had stress, anxiety and depression and psychiatry morbidity significantly associated with acne severity. Anxiety and depression were also corelated significantly with acne duration. The relationship between stress, psychiatry morbidity and acne are worth exploring as possible behaviour intervention can be useful in patients.