Background: To assess tumor control and survival of the patients with laryngeal cancers who received chemoradiation or radiotherapy alone as definitive treatment.

The main reason for the differences between the measured and calculated doses was patient movement. To reduce the risk of large errors in the dose delivered, in vivo dosimetry should be performed in addition to treatment planning system computations.

In a resource-demanding COVID-19 pandemic, guidelines can free up health care resources needed for providing better care to COVID-19 and other patients. This study was performed to design a guideline to manage patients with colorectal cancers during the COVID-19 pandemic. →What this article adds:This guideline covers the management of colon and rectal cancers in different stages, malignant polyps, and recurrent colorectal cancers during the COVID-19 pandemic. It can help achieve better care for patients with colorectal cancers in the COVID-19 pandemic. Multidisciplinary team discussions play an important role in ensuring the best treatment for patients with colorectal cancer.

A simple strategy has been developed based on 1,2-bis[5,2-thiolmethyl-sulphide-1,3,4-oxadiazol-2-yl]ethane (BTMSOE) as a novel ion-carrier for construction of a voltammetric Hg(II)-CPE. AuNPs not only have strong inter-particle binding affinity (Au-Au), but also have strong tendency to form S-Au covalent bonds with -SH functional groups. In view of this fact, by self-assembling of AuNPs, the spatial configuration of the thiol-terminated BTMSOE compound was switched from podant to macrocycletype ligand. The macrocycle-type BTMSOE-AuNP compound was then immobilized by self-assembly on the super-conductive MWCNT substrate via a (3-mercaptopropyl) trimethoxysilane (MPTS) covalent linker. Under the optimized conditions, the oxidative current I p,a (mA) exhibited a linear dependence on Hg(II) ion concentration in the wide dynamic concentration ranges of 3.5 Â 10 À11 to 3.7 Â 10 À7 M and 1.2 Â 10 À6 to 1.0 Â 10 À4 M (R 2 ¼ 0.9947 and 0.9992, respectively). Moreover, the limit of detection of the proposed sensor was 1.7 Â 10 À12 mol L À1 (S/N ¼ 3) at a working optimal pH of 4.2 adjusted by ABS as an appropriate supporting electrolyte. These features, specifically the high sensitivity and exceptional selectivity, were positively compared with those of previously reported methods in the area of electrochemical Hg(II) detection. Eventually, the practical utility of the prepared MWCNTs/AuNPs/ BTMSOE-CPE was assessed for efficient determination of Hg(II) contents in aqueous environmental samples with different matrices such as tap and mineral water, tuna fish, human hair, and tobacco.