Gender can be detected with great accuracy in gestations between 11 to 13 weeks and 6 days by using AGD. CRL and gestational week (GW) were determined as nonsignificant predictors of fetal gender by AGD measurement. In order to obtain more accurate results with AGD, consideration of further studies with larger series in different races is recommended.
Objectives: We aimed to evaluate and compare the clinical and pathological features, diagnosis, treatment, and prognosis of uterine papillary serous carcinoma (UPSC) and clear-cell carcinoma (CC).
Material and methods:Thirty-four patients who were operated on for UPSC and CC carcinoma at the İzmir Tepecik Research and Teaching Hospital, between January 1983 and December 2014, were included. Patients were evaluated for the following factors: age, gravidity, parity, preoperative CA-125, tumor size, myometrial and lymphovascular invasion, lymph node tumor metastasis, presence of atypical cells in peritoneal cytology, pathology results, operation types, whether or not they received postoperative adjuvant therapy, prognosis, and death rate.
Results:The stage of the disease was the main factor affecting disease-free and the overall survival. Cisplatin-based chemotherapy was partially effective in patients with postoperative recurrence, while postoperative adjuvant radiotherapy proved to be more effective in preventing relapse.
Conclusion:The studied parameters generally were concordant with the literature but, due to the relatively small sample size, more comprehensive and multicenter studies are needed to generate valid results.
Objective: Evaluation of the effect of platelet-rich plasma (PRP) on the endometrium and pregnancy outcomes in patients undergoing insemination due to unexplained infertility. Methods: 24 patients who were admitted to the clinic due to unexplained infertility, analyzed retrospectively between March 2018 and October 2018. Gonadotropin induction was initiated on day 3 of the cycle for follicular growth. Human chorionic gonadotropin (hCG) was applied for ovulation induction at the point that at least 1 follicle that is over 16 mm was detected by transvaginal ultrasound. 17.5 ml of blood from the patient's venous system was drawn for the preparation of the PRP which includes 4-5 times more platelets than regular blood. PRP was administered to 12 patients (Group 1) on the hCG day, while hCG was solely administered to the other group (Group 2) and both groups were inseminated 36 hours later. Results: The demographic properties of all patients were determined as follows: mean age; 29.13 years old (±3.4), mean infertility period; 1.96 years (±1.08), mean ovulation induction period; 7.92 days (±1.76), mean antral follicle count; 14.54 (±6.56), mean dominant follicle count; 2.04 (±0.75). Although there was no significant difference between the groups in terms of clinical pregnancy (3/12 vs 2/12, p: 0.623), the change in endometrial thickness was significantly higher in the PRP administered group (1.95 mm vs 0.44 mm, p< 0.001). Conclusion: PRP application before the insemination seems promising for the preparation of the endometrium in patients having an inadequate endometrial thickness or in patients experiencing recurrent implantation failure.
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