Objective: To determine the effect of combined supplementation of Pioglitazone and Acacia Honey on blood glucose levels in Streptozotocin-induced type 2 diabetic rats. Study Design: Laboratory-based animal study. Place and Duration of study: Al-Nafees Medical College, in collaboration with the National Institute of Health, Islamabad Pakistan, from Jan 2016 to Jun 2017. Methodology: The study was conducted on 150 male Sprague Dawley rats, divided into five groups with 30 rats. Group-I was the control Group. Groups II-V were given Streptozotocin 65 mg Streptozotocin intraperitoneally to make them diabetic. Group II was diabetic control. Group-III was given acacia honey for three weeks. Group-IV received an intraperitoneal injection of Pioglitazone (oral hypoglycemic) 15 mg/kg body weight per day plus Acacia honey, and Group-V was given Pioglitazone intraperitoneally for the same dose and duration. Fasting blood glucose levels were measured after three weeks of supplementation. Results: After three weeks of supplementation, the blood glucose levels were significantly (p-value <0.001) lower in all Groups (Group- III: 228.33±40.60 mg/dl, Group-IV: 132.50±22.67 mg/dl and Group- V: 120.73±14.19 mg/dl) as compared to Group-II (Diabetic Controls) (290.13±52.60 mg/dl). Conclusion: Combined supplementation of Acacia honey and Pioglitazone reduces blood glucose levels in Streptozotocin-induced type 2 diabetic rats.

Ascertain validity of a questionnaire which measures the impact of abolishment of PM&DC on Basic Medical & Dental Sciences Faculty Career Path of a Federally Chartered Public Sector Medical University. Methods: Cross sectional study conducted on a pre-defined population at a given point in time. Study setting was Army Medical College, Rawalpindi. Target population for pilot testing was basic sciences faculty of Army Medical College, Rawalpindi. 12 items questionnaire was designed using Likert scale with 5 options response set. Content validity was assured by expert opinion.Results: Inter item correlation represented by Cronbach’s alpha was p=0.839.Conclusion: The 12 item questionnaire appropriately measures the attitudes and beliefs of basic sciences faculty regarding their career path after abolishment of PM&DC