Epileptic seizure detection is commonly implemented by expert clinicians with visual observation of electroencephalography (EEG) signals, which tends to be time consuming and sensitive to bias. The epileptic detection in most previous research suffers from low power and unsuitability for processing large datasets. Therefore, a computerized epileptic seizure detection method is highly required to eradicate the aforementioned problems, expedite epilepsy research and aid medical professionals. In this work, we propose an automatic epilepsy diagnosis framework based on the combination of multi-domain feature extraction and nonlinear analysis of EEG signals. Firstly, EEG signals are pre-processed by using the wavelet threshold method to remove the artifacts. We then extract representative features in the time domain, frequency domain, time-frequency domain and nonlinear analysis features based on the information theory. These features are further extracted in five frequency sub-bands based on the clinical interest, and the dimension of the original feature space is then reduced by using both a principal component analysis and an analysis of variance. Furthermore, the optimal combination of the extracted features is identified and evaluated via different classifiers for the epileptic seizure detection of EEG signals. Finally, the performance of the proposed method is investigated by using a public EEG database at the University Hospital Bonn, Germany. Experimental results demonstrate that the proposed epileptic seizure detection method can achieve a high average accuracy of 99.25%, indicating a powerful method in the detection and classification of epileptic seizures. The proposed seizure detection scheme is thus hoped to eliminate the burden of expert clinicians when they are processing a large number of data by visual observation and to speed-up the epilepsy diagnosis.
The automatic detection of epileptic seizures from electroencephalography (EEG) signals is crucial for the localization and classification of epileptic seizure activity. However, seizure processes are typically dynamic and nonstationary, and thus, distinguishing rhythmic discharges from nonstationary processes is one of the challenging problems. In this paper, an adaptive and localized time-frequency representation in EEG signals is proposed by means of multiscale radial basis functions (MRBF) and a modified particle swarm optimization (MPSO) to improve both time and frequency resolution simultaneously, which is a novel MRBF-MPSO framework of the time-frequency feature extraction for epileptic EEG signals. The dimensionality of extracted features can be greatly reduced by the principle component analysis algorithm before the most discriminative features selected are fed into a support vector machine (SVM) classifier with the radial basis function (RBF) in order to separate epileptic seizure from seizure-free EEG signals. The classification performance of the proposed method has been evaluated by using several state-of-art feature extraction algorithms and other five different classifiers like linear discriminant analysis, and logistic regression. The experimental results indicate that the proposed MRBF-MPSO-SVM classification method outperforms competing techniques in terms of classification accuracy, and shows the effectiveness of the proposed method for classification of seizure epochs and seizure-free epochs.
The electroencephalogram (EEG) signal analysis is a valuable tool in the evaluation of neurological disorders, which is commonly used for the diagnosis of epileptic seizures. This paper presents a novel automatic EEG signal classification method for epileptic seizure detection. The proposed method first employs a continuous wavelet transform (CWT) method for obtaining the time-frequency images (TFI) of EEG signals. The processed EEG signals are then decomposed into five sub-band frequency components of clinical interest since these sub-band frequency components indicate much better discriminative characteristics. Both Gaussian Mixture Model (GMM) features and Gray Level Co-occurrence Matrix (GLCM) descriptors are then extracted from these sub-band TFI. Additionally, in order to improve classification accuracy, a compact feature selection method by combining the ReliefF and the support vector machine-based recursive feature elimination (RFE-SVM) algorithm is adopted to select the most discriminative feature subset, which is an input to the SVM with the radial basis function (RBF) for classifying epileptic seizure EEG signals. The experimental results from a publicly available benchmark database demonstrate that the proposed approach provides better classification accuracy than the recently proposed methods in the literature, indicating the effectiveness of the proposed method in the detection of epileptic seizures.
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