Background: Diabetic foot ulcers are one of the leading causes of amputation in non-traumatic patients. This research aimed to investigate the correlation between the level of HDL cholesterol and the severity level of diabetic foot ulcer based on Wagner classification. The study conducted at Wahidin Sudirohusodo Hospital, Makassar, Indonesia.Methods: This is an observational study with the cross-sectional design. The data collected before and after the treatment. The change of the levels of HDL cholesterol and the severity level of the diabetic foot ulcer based on Wagner classification during the treatment were analyzed. Data analyzed using Spearman Correlation test, the paired t-test to assess the change in the levels of HDL cholesterol and the levels of severity of diabetic foot ulcer based on Wagner classification at the time admission and after the treatment.  ANOVA test was used to observe the reduction significance of the severity of diabetic foot ulcer based on Wagner classification, and it was categorized as significant if p<0.05.Results: The results indicated that there is a correlation between the level of HDL cholesterol and the severity level of diabetic foot ulcer based on Wagner classification either at the early treatment with p-value = 0.003 (r = - 0.448) and the end of the treatment with p-value = 0.001(r = - 0.477).  The lower of the level of cholesterol HDL, the higher was the severity level of the diabetic foot ulcer. Meanwhile, the correlation between the increase of the level of HDL cholesterol and the reduction of Wagner classification during the treatment was statistically insignificant with p-value = 0.100 (r = - 0.215).Conclusions: there was a correlation between elevated HDL cholesterol levels during treatment with Wagner classification decrease during treatment, the higher the HDL change, the higher the Wagner classification, but this was weak correlation and statistically insignificant.

Nutritional status is a condition caused by a balanced between nutrient intake and nutritional requirements for metabolism. In Indonesia, the prevalence of overweight 15.1% and underweight 4.7%. This study aims to determine the relationship between physical activity and body image with nutritional status of students in senior high school of Yayasan Pupuk Kaltim Bontang. This study was an observational analytic with cross sectional study. The sampling procedure was purposive sampling according to the inclusion and exclusion criteria. The respondent of this study amounted to 262 students. The data collection being done with anthropometric measure to determine the nutritional status of students and using physical activity questionnaires to determine physical activity and body image questionnaires to determine body image. Based on bivariate analysis, there was no relationship between physical activity with nutritional status in senior high school students of Yayasan Pupuk Kaltim (p value = 1.00) and there was relationship between body image with nutritional status in senior high school students of Yayasan Pupuk Kaltim (p value = 0,000). There was 67.6% of students are normal nutritional status, 67.9% of students do moderate physical activity, and 56.5% of students with positive body image. There was not relationship between physical activity and nutrirional status and there was relationship between body image with nutritional status in senior high school students of Yayasan Pupuk Kaltim.

Cratoxylum sumatranum (Jack) Blume of the Hypericaceae family is known as "Bentaleng" by Dayak Benuaq. In ethnobotany, Cratoxylum sumatranum stems (CSS) is used as energy drink or aphrodisiac, but its effect has not been scientifically proven. The objective of this research was to evaluate the aphrodisiac activity of CSS extract by screening the aphrodisiac activity in vitro. CSS was collected from Kutai Kertanegara Regency, East Kalimantan Province. Extraction was by maceration with ethanol solvent for three days. Remaceration was done twice. In vitro screening of aphrodisiac activity used isolated rat corpus cavernosum. The organ was placed into a 10 mL chamber containing Krebs-Henselheit solution at pH 7.4, 37°C and aerated with carbogen gas. After acclimation, a contraction test was performed with phenylephrine solution and after reaching the peak of contraction at plateau the Control (solvent extract) or CSS ethanol extract was administered at cumulatively increased concentration. Vasodilation activity was known if the contraction response was decreased after the extract's administration and expressed in percent contraction with negative value. The result of this study showed that CSS ethanol extract induce vasodilatory response on rat Corpus cavernosum blood vessels. Vasodilation activity was increasing with increasing concentration of extract given compared to Control. This study concluded that CSS ethanol extract has aphrodisiac activity and it act directly through the vasodilatation of blood vessels in the rat corpus cavernosum.

Stunting adalah keadaan gagal tumbuh pada anak balita akibat kekurangan gizi kronis. Penyebab masalah pertumbuhan pada awal kehidupan disebabkan oleh masalah kurang gizi, pemberian makanan pendamping air susu ibu terlalu dini atau terlalu lambat, dan pemberian makanan yang tidak sesuai usia. Penelitian ini bertujuanuntuk mengetahui hubungan praktik pemberian makanan dengan kejadian stunting pada balita di Puskesmas Barong Tongkok Kutai Barat. Desain penelitian ini observasional analitik dengan metode kasus kontrol. Data diperoleh dari kuesioner dan data pasien di Puskesmas Barong Tongkok dengan teknik purposive samplingdidapatkan 32 kasus dan 32 kontrol. Analisis bivariat menggunakan uji chi-square dan uji fisher’s exact. Analisis data secara statistik menunjukkan tidak ada hubungan antara frekuensi makanan dengan p= 0,740 (p lebih besar 0,05), jenis makanan dengan p = 1,000 (p lebih besar 0,05), jumlah makanan dengan p = 0,545 (p lebih besar 0,05), dan praktik pemberian makanan dengan p = 1,000 (p lebih besar 0,05) dengan kejadian stunting. Tidak terdapat hubungan antara frekuensi, jenis, jumlah, dan praktik pemberian makanan dengan kejadian stunting. Pemberian makanan cukup gizi dalam jangka waktu yang pendek mengakibatkan asupan gizi tidak terpenuhi.

High cholesterol levels (hypercholesterolemia) has been Background: recognized to cause various disease, most notably the cardiovascular disease. Unfortunately, most anti-hypercholesterolemic drugs deliver several side effects for patients, by which medicinal plants have begun to attract attention for treating hypercholesterolemia. Among others, Zingiber (J.König) Link ex A.Dietr. has traditionally been taken for treating montanum health problems caused by high cholesterol levels. Hence, this work aimed at investigating anti-hypercholesterolemic effects offered by the plant. This study was conducted on 30 male Wistar rats. During Methods: