To build a lithium battery system from single cells for use in an electric drive system the coupled electrochemical and thermal characteristics of these cells have to be well-known. Otherwise it is not possible to find the best cell for a given application considering capacity, power, thermal and electric management, housing, monitoring, etc. In the presented work an easy to parameterize Simulink model regarding the electrochemical and thermal properties was developed to simulate different cell types for an electric drive system. The model is based on an equivalent circuit diagram which is parameterized by means of impedance spectroscopy as well as of current pulse techniques. Differences of these methods are discussed briefly. By comparing simulation results and measurements it is shown that the coupled electrochemical-thermal model can predict the current - voltage behaviour and the temperature development of the different cells very exactly for both constant current profiles and load profiles appropriate for an electric forklift application.
Numerous systematic reviews and meta-analyses have reported the effect of electrical nerve stimulation (ENS) on overactive bladder (OAB). However, these results are contradictory. We conducted an umbrella review to summarize the evidence and evaluate the effectiveness of ENS for OAB by using an umbrella review methodology from multiple perspectives with sufficient methodological quality. We searched the PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL and PsycINFO databases and two Chinese databases (CNKI and CBM) to identify articles written in English or Chinese that were published up to 15 February 2021. Two authors of this review independently selected the studies, assessed their quality, and extracted the data from all the included studies. We performed a quality assessment of eligible reviews using the AMSTAR 2.0 tool and estimated the summary effect size, 95% confidence intervals, 95% prediction intervals and heterogeneity. Ten systematic reviews and meta-analyses covering 89 randomized controlled trials and 16 prospective cohort studies with a total population of 5004 participants that investigated the effect of ENS for OAB in terms of 17 different outcomes were identified. ENS seems effective and safety for OAB, with our results showing weak evidence of clinical efficacy and no evidence of side effects. To recommend ENS as a practical treatment option for OAB, however, more high-quality research is needed.
Purpose
Previous literatures on the association between TLR4 gene rs4986790 polymorphism and Helicobacter pylori infection risk reported conflict results. We conducted a case‐control study and meta‐analysis to investigate whether TLR4 gene rs4986790 polymorphism confers risk to Helicobacter pylori infection.
Patients and methods
254 patients with Helicobacter pylori positive and 235 patients with Helicobacter pylori negative were enrolled. PubMed, Embase, CNKI (Chinese national knowledge internet) were carefully searched and reviewed. Odds ratio (OR) together with 95% confidence interval (CI) were applied to calculate the association power.
Results
GG genotype of TLR4 gene rs4986790 polymorphism contributes increased risk to the population of Zhejiang, China (
p
= 0.019). Meta‐analysis found that the positive findings came from Asian population by allele contrast (
p
= 0.006), homozygote comparison (
p
= 0.006) and recessive genetic model (
p
= 0.001).
Conclusion
TLR4 gene rs4986790 polymorphism is associated with Helicobacter pylori infection risk for population of Zhejiang, China. Combined with individual gene polymorphism, the accuracy of risk assessment of Helicobacter pylori infection can be improved and individualized health education can be provided for patients with Helicobacter pylori infection by nurses.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.