The existence of elements of the implementation of Minangkabau culture that became a peculiarity of the curriculum in Padang Panjang Jihad Mosque Kindergarten is interesting to be studied more deeply. Therefore, this study aims to analyze the implementation of the Minangkabau cultural curriculum related to the planning, implementation, and evaluation of learning. Qualitative research type of descriptive method. Data collection techniques on research objects are carried out through observation, interview, and observation. Data analysis starts from data reduction, presentation of data, and concluding. Assurance of data validity using data triangulation techniques. As a result of the research, curriculum planning is carried out by integrating national curriculum of 2013, PAI Curriculum, and Minangkabau cultural context. The implementation of the implementation curriculum is evident from the Daily Learning Implementation Plan (RPPH), which is integrated into the learning load. Performance, assignment (project), and observation in assessing special activities of Minangkabau culture that has become the habituation of children, especially in kato nan ampek, sumbang nan duo baleh and the art of Minangkabau tradition

Tuberkulosis merupakan penyakit menular yang menjadi penyebab kematian tertinggi di dunia. Provinsi Jawa Barat merupakan provinsi dengan jumlah kasus TB Paru tertinggi di Indonesia. Diantara berbagai faktor yang memengaruhi kejadian TB adalah aspek keruangan. Penelitian ini merupakan studi ekologi yang bertujuan mengetahui hubungan dan autokorelasi spasial kejadian TB Paru BTA positif dengan variabel sosiodemografi dan variabilitas iklim di Provinsi Jawa Barat tahun 2013-2017. Analisis data dilakukan dengan uji korelasi Spearman, Moran’s I, LISA, dan BiLISA. Hasil penelitian ini menunjukkan tidak terdapat autokorelasi spasial Kejadian TB Paru di provinsi Jawab Barat. Hasil analisis bivariat LISA (BiLISA) menunjukkan terdapat autokorelasi spasial lokal pada variable Rumah Sehat di tahun 2013 TB Paru BTA positif dengan pola acak. Tidak terdapat autokorelasi spasial antara factor sosidemografi lainnya dengan  Kejadian TB Paru positif. Diharapkan kepada Dinas Kesehatan untuk meningkatkan upaya penemuan kasus dan meningkatkan promosi kesehatan terkait penyakit TB Paru, rumah sehat dan perilaku hidup bersih dan sehat pada daerah-daerah dan masyarakat yang berada di lokasi berisiko.

The purpose of the current study is to explore the prominent role of the fixed oil of Citrullus colocynthis seeds as a natural remedy to obesity. Wistar rats were subjected to different diets; one being an 8 week high-fat diet that was established to induce obesity in rats. The results from our experiment show a significant correction in body weight, blood parameters, and in particular, the total cholesterol, triglycerides, HDL-C (high-density lipoprotein cholesterol), and glycemia. There was also an improvement of the redox status shown by the significant increase in antioxidant vitamins levels and decrease in malondialdehyde contents as well as an increase in the hepatic enzymes activities in Citrullus colocynthis seeds oil treated rats compared to obese rats and olive oil treated rats. The results of this study demonstrated that Citrullus colocynthis seeds oil prompted a corrective effect in the antioxidant defense systems, restored insulin sensitivity, and improved lipid profile. To conclude, our study suggests that Citrullus colocynthis seeds oil is a promising natural tool to combat obesity and its associated complications.

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The present work was aimed at evaluating antifungal effect of the fraction of fatty acids methyl esters isolated from the seeds of Citrullus colocynthis against two toxigenic fungal strains (Aspergillus flavus and Aspergillus ochraceus). The evaluation of antifungal activity was carried out by two methods: the radial growth solid medium and the evaluation of the biomass liquid medium. The seeds understudy provided acceptable yields of oils and esters. The characterization of these oils and their corresponding methyl esters was carried out by spectroscopic analysis. The reading of the GC/MS spectrum revealed the richness of these oils in α-linolenic acid and linoleic acid. The results of the antifungal activity showed that the crude esters and their corresponding major esters have exhibited a pronounced antifungal power. This effect was very important on the solid medium and more pronounced for A. flavus. The major esters provided the best antifungal index [IAF = 51.67±0.40 % A. flavus, IAF A. ochraceus = 35.58 ± 0.37 %] compared to crude esters [IAF A. flavus = 48.64 ± 0.28 % IAF A. ochraceus = 28.37 ± 0.17 %]. These finding suggest that Citrullus coloquinthis L. seeds are an interesting source of fatty acids methyl esters having antifungal potentialities allowing them to be used as preservative compounds against toxigenic fungi.