Melissa A. Knopf scite author profile

Calcitonin gene-related peptide (CGRP) is a sensory neuropeptide with inflammatory and immunoregulatory activities. Its role in B lymphocyte development was investigated using a pre-B cell colony-forming assay. Physiological concentrations of CGRP inhibited pre-B cell responses to interleukin-7 (IL-7). Inhibition was specific in that it was blocked by the CGRP antagonist CGRP 8-37 . Adrenomedulin, substance P, and calcitonin had no

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Calcitonin gene-related peptide indirectly inhibits IL-7 responses in pre-B cells by induction of IL-6 and TNF-α in bone marrow

Fernandez

Knopf

Shankar

et al. 2003

Cellular Immunology

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Calcitonin gene-related peptide induces AP-1 activity by a PKA and c-fos-dependent mechanism in pre-B cells

McGillis

Miller

Schneider

et al. 2002

Journal of Neuroimmunology

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Chlorpactin instillation releases calcitonin gene-related peptide in interstitial cystitis patients

Kreder

Lutgendorf

Knopf

et al. 2001

Urology

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Melissa A. Knopf

Bone Marrow-Derived Macrophages Express Functional CGRP Receptors and Respond to CGRP by Increasing Transcription of c-fos and IL-6 mRNA

Calcitonin-gene related peptide (CGRP) inhibits interleukin-7-induced pre-B cell colony formation

Calcitonin gene-related peptide indirectly inhibits IL-7 responses in pre-B cells by induction of IL-6 and TNF-α in bone marrow

Calcitonin gene-related peptide induces AP-1 activity by a PKA and c-fos-dependent mechanism in pre-B cells

Chlorpactin instillation releases calcitonin gene-related peptide in interstitial cystitis patients

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