ndometrial cancer is the most common cancer of the female reproductive system in the United States and developed world. 1,2 The American Cancer Society estimates 65,950 new cases of uterine cancer (endometrial cancers and uterine sarcomas) in 2022. 1 This is an increase of 6.6% from 2019. 3 Risk factors for endometrial cancer include advancing age, early menarche, nulliparity, late menopause, hormone replacement therapy, obesity, type 2 diabetes, polycystic ovarian syndrome, and genetic disorders such as Lynch syndrome. 4 The average age of diagnosis is 60 years. 1 The most common clinical presentation of a woman with endometrial cancer is abnormal postmenopausal vaginal bleeding. 4 Physical examination fi ndings are limited, because peritoneal abnormalities and adnexal masses are more indicative of advanced disease. 4 At the time this article was written, Lacey King was a student in the