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In this retrospective, interventional case report of a 40 year-old woman with Stickler Syndrome, we present a novel use of dermis fat graft to manage an externally exposed scleral buckle that was refractory to other methods of management. Dermis fat graft is a relatively robust material that can be effectively utilized to rescue an exposed scleral buckle. This case presentation conforms to the tenets of the Declaration of Helsinki and is Health Insurance Portability and Accountability Act compliant. This single patient case report was institutional review board exempt as it does not meet the definition of human subjects' research.Keywords: Scleral buckle; Stickler syndrome; Dermis fat graft; Retinal detachment SummaryWe describe a novel use of dermis fat graft to successfully manage a repeatedly exposed scleral buckle that was refractory to conventional management in a woman with Stickler Syndrome.