Granular cell tumor (GCT) also known as Abrikossoff’s tumor is a benign neoplasm that is usually seen in the fourth to sixth decades of life with slight female preponderance. It is most frequently seen in the oral cavity, skin, and subcutaneous tissue. Gastrointestinal tract involvement is uncommon, in which esophagus is the most commonly affected site. There are case reports of GCT in stomach, appendix, colon and rectum. In this article, we report a case of GCT involving cecum. The cell of origin in GCT is controversial. There are various pools of thoughts regarding its histogenesis, the details of which are reviewed in this article with emphasis on the diagnostic difficulties encountered in this tumor.

Light chain cast nephropathy is the most frequent form of renal disease in plasma cell neoplasm showing precipitation of monoclonal immunoglobulin light chains in the lumen of the distal tubules. This has a typical morphological feature characterised by the presence of a fractured cast. In this article, we report an unusual case of light chain cast nephropathy exhibiting amyloidogenic potential with lamellated, spiculated appearance. These casts were positive for periodic acid–Schiff and Jones’ silver stain, fuchsinophilic in Masson trichrome stain and showed apple-green birefringence under polarised light in Congo red stain. Complete haematological evaluation confirmed the presence of underlying plasma cell myeloma. The connotation of intratubular amyloid cast lies in the fact that this may represent an early phenomenon during the development of light chain cast nephropathy-associated systemic amyloidosis and may precede the formation of light chain amyloid in renal or extrarenal location.

Abstract:The Jatadharmohan creek lies between Mahanadi and Devi Rivers along the Orissa coast and it is separated from the sea by an elongated sand spit. It was proposed to mine a volume of 15 x 10 6 m 3 of sand from the creek for land filling, but maintaining the spit intact. For this, the stability of sand spit is studied with different criteria. The results confirm that the creek mouth is a near permanent zone of deposition. The model results obtained for various depth scenarios show that the magnitude of currents would increase considerably when depth is increased by 7.0m and marginally for further increase in depth by 10.0m. Accordingly, a dredging scheme has to be designed without affecting the spit stability. Considering the existing hydrodynamics in the creek system, it is recommended that a bed slope of 1:6 (9.5°) be maintained during dredging, which is much less than 13.75° -the evaluated critical slope at the site when seepage flow is parallel to the bed slope. It is observed during monitoring that the creek is very productive, and the sand spit is totally intact.

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Primary pulmonary lymphoma is defined as clonal lymphoid proliferation affecting one or both lungs in a patient with no extrapulmonary involvement at the time of diagnosis or during the subsequent 3 months. Anaplastic large cell lymphoma (ALCL) is a rare T-cell neoplasm which occurs as two distinct clinical entities-cutaneous and systemic variant. Primary lung involvement is extremely uncommon. It can be classified on the basis of being positive or negative for ALK rearrangement which carries prognostic significance. The 2016 revision of World Health Organization (WHO) classification of lymphoid neoplasm recognizes three types of ALCL namely ALK-positive, ALK-negative, and breast implant associated. Here, we report a case of primary pulmonary ALK-1 positive ALCL which was initially recognized in bronchial brushing cytology based on distinct morphologic clues.