The Occupied Territories of Palestine (OtP) consists of the non-contiguous West Bank including East Jerusalem, and the Gaza Strip. Its dense population with political and economic tensions is affected by a rise in drug trafficking, abuse and addiction. A scoping review mapped what is known about Palestinian children's experiences of drug abuse in the home. Following application of exclusion measures, six records remained. Charting and analysis resulted in three themes; The consequences of being a child with a drug using parent; Causal factors of drug use in Palestinian families; and Prevalence rates of parental drug use are unknown. The review paints a concerning picture of stigma, family dysfunction, school drop-out, child and family isolation and maladaptive child development. Exposure to drugs, trauma and abuse contributes to strong potential for Palestinian child drug use, sexual exploitation, overdose, psychiatric illness, and infectious diseases acquisition. The review will inform the urgent strategic response. Abstract 3 The Occupied Territories of Palestine (OtP) consists of the non-contiguous West Bank including 4 East Jerusalem, and the Gaza Strip. Its dense population with political and economic tensions is 5 affected by a rise in drug trafficking, abuse and addiction. A scoping review mapped what is known 6 about Palestinian children's experiences of drug abuse in the home. Following application of 7 exclusion measures, six records remained. Charting and analysis resulted in three themes; The 8 consequences of being a child with a drug using parent; Causal factors of drug use in Palestinian 9 families; and Prevalence rates of parental drug use are unknown. The review paints a concerning 10 picture of stigma, family dysfunction, school drop-out, child and family isolation and maladaptive 11 child development. Exposure to drugs, trauma and abuse contributes to strong potential for 12 Palestinian child drug use, sexual exploitation, overdose, psychiatric illness, and infectious 13 diseases acquisition. The review will inform the urgent strategic response.14