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The long term goal of the project is to automate the screening for diabetic retinopathy with retinal images. We have described the preliminary development of a tool to provide automatic analysis of digital fundus photographs to localise hard exudates. Future work will address the issue of improving the obtained results and also will focus on detecting other lesions.

Purpose The aim of this study is to present the results of pars plana vitrectomy in patients with advanced disease and to identify preoperative risk factors and postoperative visual outcome. Methods The study was carried out at the University Hospital in Valladolid (Spain) with data from patients throughout two years. Results Retrospective chart review of patients who underwent posterior plas plana vitrectomy (PPV) during 2010‐2011 for non‐clearing vitreous haemorrhage (NCVH), tractional retinal detachment (TDR) or diabetic edema with vitreomacular traction (TME) and followed for at least 6 months.The primary outcome measure was the best corrected visual acuity (BCVA) at the end of the follow‐up period and its correlation with preoperative risk factors.The secondary outcomes were postoperative complications and the influence of the status of the external retina in the ocular coherence tomography (OCT). 58 patients underwent PPV for advanced retinal disease. NCVH was the most frequent surgical indication in 32 patients and 21 of them had gone through laser previously. Mean preoparative BCVA was 1.96 ± 1.13 logarithm of minimum angle of resolution (logMAR) units and it improved.TDR was the indication in 10 patients. Only 50% of them had laser and all of them suffered from long term disease. There was not significant improvement in the BCVA and 3 patients developed neovascular glaucoma. Ind Conclusion Preoperative BCVA, long term disease, the lack of laser treatment and the external retina seem to be some of the most important risk factors in these patients.

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Purpose: To asses the efficacy of intravitreal Triamcinolone Acetonide (TA) in diffuse diabetic macular edema (DME) refractory to laser coagulation Methods: Descriptive, retrospective, non randomized study without control group done on 35 eyes of 27 patients with DME and negative dexamethasone test, treated with 4mg intravitreal TA between January‐2006 and March‐2007. Variation in Visual Acuity (VA)(Snellen Chart) was considered as main outcome, and angiographic (AFG) edema was consider as secondary outcome. The statistic analysis was performed by contingency tables, Chi‐square test and Fisher exact test Results: The median basal VA was 0.16, observing an improvement of two or more lines in 31.4% at first month post op and 34.3% at the end of follow up(7 months). Although the edema was resolved in 42.9% at the first month by AFG, it persisted in 77.1% by the end of the study. A mayor effect was observed in patients treated with insulin+oral hypoglucemiants+diet(p:0.021), cystic CSME(p:0.018), or previous grill laser(p:0.055).A statistically significant relation was observed between VA and the absent of edema in the AFG. Three eyes developed ocular hypertension during the first 24 hours and 4 eyes at first month, all them controlled by topical treatment. No endophthalmitis was observed Conclusions: Results were similar to bibliography. A strong relation was observed between VA and AFG during entire follow up. Systemic treatment with diet‐insulin‐oral hypoglucemiants seemed to induce a better respond to the intravitreal TA in the control of DME