complex. The average loading efficiency of DOX was 35% for NFHFCNP and 41% for HFCNP, respectively. In drug release profile, the release rate of DOX from the nanocomposite was increased with respect to time. The cell lines, KB and A549 treated with 68 Ga(NF)HFCNP showed high cell viability and excellent cell uptake. Meanwhile, the DOX-loaded nanocomposites exhibit high cytotoxicity toward these cell lines. These properties make 68 Ga(NF)HFCNP nanocomposite as a potential dual theragnostic probe for PET/MRI and targeted chemotherapy for cancer cells.
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