Objectives In Egypt, the National Cancer Registry Program integrates hospital-based data from multiple Egyptian governorates to obtain representative rates. Unfortunately, Dakahlia (one of the largest Egyptian governorates) was not integrated in the National Cancer Registry Program. This research aimed to acquire malignancy rates from the Oncology Center of Mansoura University, which is one of the two oncology centers present in Dakalia Governorate in Egypt. Methods Electronic records of patients who attended the Oncology Center of Mansoura University during 2016 were accessed with permission. Analysis was performed to extract diagnostic categories (age, gender, and geographic distribution of cases). Results Most commonly diagnosed malignancies were breast cancer which represented about 10% of cases in the Oncology Center of Mansoura University during 2016. This was followed by leukemia (3.80%), lymphoma (3.59%), and liver cancer (3.44%). Diagnoses encountered included benign and malignant tumors as well as non-tumor diagnoses. The Mansoura district had the highest proportionate rate of breast cancer cases. Females in the age group ≥ 35 < 60 years had the highest incidence of malignancy cases across all diagnoses. Conclusion The burden of breast cancer in Mansoura district is high. Risk factors need further evaluation with a recommendation to perform an environmental risk assessment.

Background Depression significantly impairs all aspects of the patient’s life. Work comes on top of the list. This greatly affects productivity nationally and internationally. This study aimed to determine work impairment among patients with depression, and its associated factors. Methods This is an observational descriptive cross-sectional study conducted on 380 patients with depression who attended Mansoura University Hospitals, Egypt. Depression diagnosis was based on structured clinical interview using Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and Young Mania Rating Scale (YMRS). Data were collected using a questionnaire. Sociodemographic, occupational, and clinical factors were inquired about. Lam Employment Absence and Productivity Scale (LEAPS) was used to calculate work impairment in patients with depression. Results more than half of the study participants (52.4%) had moderate, severe, or very severe work impairment. Independent predictors of moderate to very severe impairment are insufficient income, morning shift work, missed 5 or more work hours during the past 2 weeks, Hamilton Depression Rating Scale (HDRS) of 25 or more, 2 or more depressive episodes, 5 or more depressive symptoms, and death thoughts. Conclusions Depression greatly impacts patients’ ability to work. Periodic screening for work impairment especially among high-risk groups allows for early detection and timely intervention to reserve quality of life and work performance.