A tube latex agglutination test (LAT) for diagnosis of Mycoplasma hyopneumoniae swine pneumonia was developed. In M. hyopneumoniae inocu lated pigs, LAT antibodies were generally detected 2 to 3 weeks postinoculation, which was 1 week or more before complement-fixation anti bodies were first detected in the corresponding pigs. Correlation of LAT results and gross and microscopic lung lesions of corresponding pigs re vealed that LAT titers persisted after the pneumonic lesions had resolved. Latex agglutination titers in contact exposed pigs were demonstrated 4 to 12 weeks post-contact with M. hyopneumoniae inoculated pigs. Latex agglutination antibodies were detected up to 48 weeks postinoculation in M. hyopneumoniae inoculated pigs which was similar to the
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