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ChemInform Abstract Reaction of the aminothiophenecarboxylates (I) with the isothiocyanate (II) yields the thioureas (III) which are cyclized under acidic conditions, forming the thienothiazines (IV). Their antiallergic activity is determined.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

3,5,5-Trisubstituted Hydantoins from Activated (Benzyloxycarbonylamino)malonic Acids. -Trisubstituted hydantoins (VI) are obtained in low yields from malonic acid derivative (IV) via activation with oxalyl dichloride and subsequent treatment with aromatic amines. The origin of the aldehyde group in the second products (VII) remains unclear. -(HROCH, L.; HRUSKOVA, M.; SCHMITZ, J.; SCHNAKENBURG, G.; GUETSCHOW*, M.; Synthesis 2012, 12, 1907-1914, http://dx.doi.org/10.1055/s-0031-1290974 ; Inst. Pharm. Chem., Rhein. Friedrich-Wilhelms-Univ., D-53115 Bonn, Germany; Eng.) -Mais 39-137