In the absence of large, comparative randomized clinical trials, the minimally invasive techniques appear to be at least as effective as surgery in the treatment of lower extremity varicose veins.

After 1-year follow-up, EVLA is as effective as CS and superior to UGFS according to occlusion on ultrasound duplex. Quality of life improves after treatment in all groups significantly.

NCT00529672 (http://www.clinicaltrials.gov).

EVLT appears to be a very effective and safe option in the treatment of varicose veins but large randomized comparative studies are needed.