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Bubble formation in a microfluidic flowfocusing device is simulated using the volume-of-fluid approach to achieve a complete solution of the NavierStokes equations for both the gas and liquid phases. The results of the simulation show good agreement with previous experimental results. A detailed examination of the predicted pressure and velocity profiles from the simulation also provide further validation for the conclusions drawn previously with experimental results. The simulation results show the existence of two distinct modes of bubble formation. Simulations of systems an order of magnitude smaller than those investigated experimentally indicate that such reduced systems sizes are a viable approach that would result in much smaller bubble sizes.

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