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The ear is divided into three parts: the external ear, middle ear, and internal ear. The external ear is a funnel-shaped structure that channels air vibrations to the tympanic membrane. It consists of the auricle (pinna) and the external ear canal (external acoustic meatus) that extend to the tympanic membrane. The structure of external ear canal is both cartilaginous and osseous. Some hair and many tubular ceruminous and sebaceous glands are present in the canal. Their secretions forms cerumen, a mucilaginous fluid containing brown granules. Two surgical techniques are available for the treatment of neoplasms of the external canal: the lateral resection, for small neoplasm's nodules of the canal; and the ablation of the ear canal, operation of choice when the neoplastic mass is deep and extensive, within the ear canal. It describes the case of a male dog, Cocker Spaniel, ten years old, patient treated in Surgery, Faculty of Veterinary and animal Sciences, University of Chile, with an episode of external otitis and a tumor that involved the right ear pinna and external right ear canal. It was decided proceeded taking samples for biopsy and subsequently to perform the removal of the external ear canal. The histopathologic diagnosis was ceruminous gland cell carcinoma.

The objective of this work was identify the presence of interstitial cells of Cajal, muscle cells, nerves and androgen receptor positive cells in adult human testicle, using immunohistochemical detection for c-kit/CD-117, actin smooth muscle specific (ASMS), neurofilament (N) and androgen receptor (AR), respectively. The samples were obtained from patients (n= 10) with diagnosis of prostate cancer, with surgery of orchiectomy. Subsequently were processed by histology and for immunohistochemistry using specific antibodies. It showed the presence of cells c-kit/CD-117, with diverse degrees of positivity, distributed mainly in the interstitial peritubular area of the human testicle. The peritubular myoides cells were positive to the presence of the actin smooth muscle and androgen receptor. The neurofilaments elements (+) only were observed in the vascular tunic. The specific immunohistochemistry describe the presence of the interstitial cells of Cajal in human testicular interstitium, opening a new perspective for the functional interpretation of the testicular cellularity and tubular motility. Possibly associated functionally to peribubulars cells of smooth muscle to regulate the mobility of the seminiferous tubules, whose integration and function would be androgen dependent. The cells that express the c-kit receptor, were found exclusively in the interstitial compartment. This cellular type in addition of the muscular cells of peritubules and the absence of nervous fibers to the interior of the testicle, could be responsible for the regulation of tubular mobility, as it happens in the gastrointestinal apparatus.

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