"Leiomyosarcoma is a rare type of smooth muscle cell tumor, with an incidence of 7-10% compared to other types of sarcomas. It develops primarily in the retroperitoneal cavity, the genital tract and extremities. Leiomyosarcoma can also affect the bone, either as a primary tumor or as metastasis. Primary osseus leiomyosarcoma is a rare finding in patients with radiologically identified osteolytic lesions having an incidence of <1% of total primary bone tumors.Due to its low incidence patients with primary osseous leiomyosarcoma are never diagnosed before immunohistochemical analysis and case management is difficult because of the lack of specific indications pertaining to primary osseus leiomyosarcoma. Data on age specific incidence is scarce but there seems to be a tendency towards a higher incidence with advanced age. The purpose of this work is to discuss the complete management of primary osseus leiomyosarcomas based on interdisciplinary medical teams’ indications in a Romanian hospital setting"
This paper explores an overlooked aspect of the brief but intense correspondence between William Petty and Henry More, making use of the Hartlib Papers Online. Traditionally, the brief epistolary exchange between More and Petty has been seen in the light of an opposition between Cartesian rationalism and Baconian empiricism. A look at the original manuscripts, however, shows that the opposition was not originally framed in those terms at all. This article draws attention to the actors’ original categories, and places this exchange in the evolving landscape of seventeenth-century natural philosophy.
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