Seven triterpenes, ␣-amyrin (1), uvaol (2), ursolic acid (3), ␤-amyrin (4), erythrodiol (5), lupeol (6) and betulin (7), two sterols, ␤-sitosterol (8) and ␤-sitosterol 3-O-␤-glucopyranoside (9), and one flavonoid, syringetin 3-O-␣-rhamnopyranoside (10) were isolated from the methanol extract of the fruit of rabbiteye blueberry (Vaccinium ashei). Their chemical structures were determined on the basis of spectroscopic data. Among them, 3, 4 and 9 exhibited moderate growth inhibitory activity against human lung cancer cells (PC-12) and human colon cancer cells (HCT116) using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.

A new ortho-benzoyloxyphenyl acetic acid ester, called vaccihein A (1), was isolated from the fruit of rabbiteye blueberry (Vaccinium ashei). The chemical structure was determined on the basis of spectroscopic data. Compound 1 had antioxidative activity using the ferric thiocyanate method. In addition, 1 showed a scavenging effect on the stable free radical 1,1-diphenyl-2-picrylhydrazyl.Key words Vaccinium ashei; blueberry; Ericaceae; benzoyloxyphenyl acetic acid ester; vaccihein A; antioxidative activity 1416 Notes Chem.

Other natural productsOther natural products U 0800Antioxidant ortho-Benzoyloxyphenyl Acetic Acid Ester, Vaccihein A, from the Fruit of Rabbiteye Blueberry (Vaccinium ashei). -[isolation and structure elucidation of title compound (I), which shows moderate antioxidative activity and a scavenging effect on the stable free radical 1,1-diphenyl-2-picrylhydrazyl]. -(ONO*, M.; MASUOKA, C.; KOTO, M.; TATEISHI, M.; KOMATSU, H.; KOBAYASHI, H.; IGOSHI, K.; ITO, Y.; OKAWA, M.; NOHARA, T.; Chem.