It is shown that the micropolar medium is a continuum approximation to large grid frameworks under initial axial forces. The strain energy, equilibrium conditions and boundary conditions are formulated, and some inconsistencies in the previous attempts of derivation of the micropolar analogy for gridworks are pointed out. The finite difference method, which is one possible means for the analysis of the overall behavior of a large framework, is investigated and found, by means of numerical examples, to give rather accurate results using much fewer unknowns than the exact analysis. The method is also applicable to problems of overall buckling. It is shown further that the so-called substitute frame in general does not exist, although the finite difference method serves the same purpose. Finally, it is demonstrated that in micropolar continua there exist certain boundary disturbances which rapidly decay with distance from the boundary. A simplified treatment of such disturbances is proposed.
The results of this study indicate that the Test Product significantly reduced corneal and conjunctival staining, indicating a reduction in disease severity. Evaluations of ocular staining scores provide clinically meaningful evidence of dry eye severity and are an important indicator of dry eye disease progression.
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