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A novel downlink transmission selection scheme based on the locations of users for network coded cache-enabled, Multiple-Input Multiple-Output (MIMO) systems is proposed in this paper. Caches are available at both base stations (BSs) and mobile terminals (MTs) and network coding is employed in order to reduce power consumption. We compare the analysis of the proposed scheme with a simple direct transmission scheme in terms of achievable sum rate and outage probability. It is shown that the proposed scheme is preferred for high transmit signal-to-noise ratio (SNR) and/or high cross-link channel gain ratio scenarios, while the simple direct transmission scheme is better for low SNR and/or low cross-link channel gain ratio. Motivated by this analytical results, we present a selection algorithm for location-aware transmission scheme for two-cell networks. Numerical results confirm our theoretical analysis. INDEX TERMS Wireless caching, achievable sum rate, outage probability.

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Egfl7 encodes a secreted protein that is part of the interstitial extracellular matrix. Its embryonic expression is restricted to the sites of mesodermal precursors of angioblasts, the vascular endothelium in the embryo proper and the yolk sac. In mice that lack Egfl7, 50% die in utero of unknown causes. Because loss‐of‐function studies have not provided a clear role for this factor, we generated EGFL7 transgenic mice to elucidate its function in vivo. In these mice, EGFL7 is overexpressed in endothelial and hematopoietic cells, under the control of the Tie2 promoter. EGFL7 transgenics are both viable and fertile; however, at E12.5 they show hemorrhaging and vascular remodeling defects, which are accompanied by a lower than expected Mendalian ratio. At E10.5, EGFL7 transgenics exhibit vessel fusion and aberrant endothelial cell clusters in the head vasculature that is not apparent in wild types. At E12.5, transgenics show enlarged vessel lumen and an impairment in vascular smooth muscle cell recruitment. Remodeling defects are also evident in other vascular beds. 20% of E12.5 yolk sacs show similar defects to those observed in the head. Likewise, post‐natal transgenic retinal vasculature exhibits remodeling defects and an increase in vascular coverage. Together, our gain‐of‐function studies show that EGFL7 controls vascular remodeling in several vascular beds in vivo, uncovering a novel role for EGFL7.