The software of the geographical information system for studying the Earth's natural disasters (GIS-ENDDB) is focused on the research into cause-and-effect relations of catastrophic events in our planet's history. It contains data on the Earth's seismic activity, anomalies of heat flows (HF), gravitational field and tomography layers, detailed geographical relief, as well as data on cosmogenic structures distribution. To develop methods for analyzing these data, it has been added into the subsystems of information and mathematical software updates such as: the algorithm for building seismicity lineaments in terms of the Great circles (GC) of the Earth; the algorithms for constructing the contours of a maximum earthquake magnitudes and of the averaging earthquake mechanisms; the functions of geophysical fields visualization and the cross-section visualization of different seismicity characteristics; and tomography data. All these updates help to extend the capabilities of classical methods for geotectonic studies by a complex scientific-experimental approach allowing one to reveal tectonically active faults, to study the spatial relationship of seismicity and cosmogenic paleostructures (related to the historical past of the Earth), and, eventually, to interpret the data in terms of constructing seismic-geodynamic models of the lithosphere.

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Peptic ulcer is a widespread disease. This chronic progressive disease is caused by many factors, including vegetative imbalance and atherosclerosis. The purpose of this research was to estimate the effectiveness of application of low intensity laser radiation in complex treatment of patients with peptic ulcer and erosions of digestive tract and atherosclerosis. There were 44 patients in main group. 14 patients had erosions and 30 had ulcer of mucous. Control group consisted of 23 patients. There were 21 patients in placebo group. Laser therapy was performed using the device «Matrix». Lipid state was examined in all patients. It was established that in the main group the pain and dyspeptic syndrome decreased earlier than in other groups. Laboratory studies have shown that in the main group was significantly earlier improved biochemical indices of blood: cholesterol decreased by 2.48±0.4 mmol/l (p<0.05), total lipids by 4.5±0.7 g/l (p<0.05), triglycerides by 2.4±0.8 mmol/l (p<0.05), b-lipoproteins by 2,4±0,3 mmol/l (p>0.1). After treatment in the proposed method the certain improvement of time and spectral indices of IVS were identified. This method of treatment allows to increase the effectiveness of therapy, time of treatment and to correct lipid imbalance and vegetative status as well as to reduce dose of drugs.

Metabolic disorders and dysfunctional state of the digestive organs lead to the development of distal extremities diseases. The greatest danger is neсrobacrillosis. Vaccination is one of the ways to prevent and control this disease. The article reflects the data on the effect of vaccination (“Nekovak” and formol-emulsion neсrobacrillosis vaccine of Federal Centre for toxicology, radiation and biological safety) on immunological and serological parameters of blood and blood serum of cattle in the Udmurt Republic. After immunization with “Nekovak” vaccine and formol-emulsion neсrobacrillosis vaccine, we determined an increase of the number of leukocytes to 7th day, and also an increase of T-lymphocytes to 14th day. The number of B-lymphocytes reaches a maximum on 21st day. The content of gamma globulins, including specific antibodies against the neсrobacrillosis pathogen, exceeded the control and reached a maximum on the 21st day after vaccination.