Background: In the days of the reorganization of healthcare systems due to SARS-Cov2 pandemic, patients suffering from chronic diseases are being often neglected. The aim of our study was to examine the attitudes and behaviors of patient suffering from relapsing-remitting form of multiple sclerosis using disease-modifying drugs in Montenegro in relation to the current pandemic. Methods: The research was conducted through an online-generated questionnaire during the peak of the pandemic.Results: There is a high level of concern about COVID-19 (3.22 ± 1.23), especially about safety behavior intensification (3.80 ± 1.29). Possibility of relapse during pandemic was considered as moderate (2.06 ± 1.42), but relapse symptoms would be reported by the majority of subjects (1.55 ± 1.23). Our unemployed patients statistically more often reported that they had more frequent mood changes, but also that they felt more energy loss. Surprisingly, there was no difference among the subjects according to smoking status. According therapy groups there was significant difference between the groups regarding some variables: patients using ocrelizumab are most concerned about COVID-19; patients using interferon beta 1a i.m. statistically more often have frequent changes in their mood, memory problems, poor appetite, feeling of nausea or upset stomach and patients on fingolimod have bigger afraid of coming to regular visits. Conclusion: Our patients showed concern about their disease future status in the current epidemic era, but also showed a high degree of trust in physicians and the overall health system.
Shortly after the outbreak of the COVID-19 pandemic, there was a need to provide protective equipment to the medical facilities whose supplies were threatened to be depleted. Just like many countries in Europe, Montenegro responded to the need for medical equipment by using the advantages of 3D printers while establishing a state network of production hubs, ensuring closed connectivity, communication, and the mutual fulfilment of personal protective equipment (PPE) demands whenever and wherever required. With the second wave of the pandemic, Montenegro rose to second place in the world with the number of coronavirus cases, which also led to an increasing number of infected medical staff. Since fever is a frequent symptom of SA+RS-CoV2 infection, a type of innovative 3D-printed thermo-sensored medical gear has been designed and tested in hospital conditions. This medical gear shaped like a bracelet, which changes color in the presence of high human body temperatures, proves to be efficient and easy to use for medical staff as well as patients.
Introduction: Sudden cardiac death has a tendency to increase among elite athletes. It has been reported that endurance exercise increased serum concentrations of cardiac biomarkers in elite athletes although it is unclear whether is clinically significant or is a part of the physiological response. Lately, the theory of myocardial stunning is attractive since there is no permanent cellular damage and is transient nature. This prompts us to evaluate the significance of Hsp27 and GP-BB as sensitive and specific biomarkers of myocardial stunning in elite male water polo players. Materials and methods: A prospective and experimental study included 20 elite male water polo players, randomly divided into two groups that matched for age, length of active practicing water polo and level of physical stamina. Blood samples for testing were obtained at the following time points: baseline, 1, 30 and 60 min following exercise as well as for control group. Results: Endurance exercise has resulted in an increased serum concentration of Hsp27 at 50% after 1, 60% after 30 and 80% of water polo players after 60 min. Simultaneously, serum concentration of GP-BB were increased in 40% of water polo players after 1 min as well as for 10% after 30 and 60 min. Further analysis has established significantly positive correlations among obtained serum concentration of Hsp27 and GP-BB at 1 (p<0.05) and 30 (p<0.01) min. Conclusion: Serum concentration of Hsp27 could be important indicator of the risk assessment and prevention of developing heart damage in water polo players or for athletes in general. Positive correlation between Hsp27 and GP-BB indicating the reversibility damages of structural and contractile proteins in myocardial cells. Further investigation is needed to investigate connection to oxidative stress as a significant part of metabolic exhaustion of myocardial cells.
Objectives: To perform screening of dysphagia in Montenegrin multiple sclerosis )MS( patients. Dysphagia is often neglected problem in patients with MS. Methods:We included 104 patients with relapsingremitting MS who completed 3 questionnaires: dysphagia in multiple sclerosis )DYMUS(, eating assessment tool-10 )EAT-10( and swallowing disturbance questionnaire )SDQ(. Our study was performed in the clinic for neurology of the Clinical
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