Objective Among the noncommunicable disease, cancer is one of the highest load and charge that lead to disability and death. The goal of this study was to determine the important epidemiologic factors that effect on survival rate of patients with laryngeal cancer. Methods From 307 cases, 136 (2009-2012) that their follow-up was possible by phone or postal address were included in the study. Data collections were performed from the questionnaire. The data were analyzed by SPSS version 20. The Kaplan-Meier survival curves were utilized and, moreover, the corresponding influential factors were examined by using the Cox regression test. Results The most widely used method for the treatment was a combination of three methods of surgery, radiation therapy, and chemotherapy. The overall 5-year survival rate was 47.28%. The age and regular follow up had a statistically significant relationship with the survival rate (P = 0.02, 0.03). Conclusion The survival rate was lower in older patients. Patient and professional delays were high, which need more attention for improving the quality of life.